Biology Faculty Articles
Submissions from 1988
Developmental Competence of Domestic Cat Follicular Oocytes after Fertilization In Vitro, K. L. Goodrowe, R. J. Wall, Stephen J. O'Brien, P. M. Schmidt, and David E. Wildt
The κ-Deleting Element: Germline and Rearranged, Duplicated and Dispersed Forms, Winfried B. Graninger, Paula L. Goldman, Cynthia C. Morton, Stephen J. O'Brien, and Stanley J. Korsmeyer
Report of the Committee on Comparative Mapping, P. A. Lalley, M. T. Davisson, J. A. Graves, Stephen J. O'Brien, T. H. Roderick, D. P. Doolittle, and A. L. Hillyard
Chromosomal Localization of Satellite DNA Sequences Among 22 Species of Felids and Canids (Carnivora), William Modi, T. G. Fanning, R. K. Wayne, and Stephen J. O'Brien
Chromosomal Localization of the Human Interleukin 1α (IL-1α) Gene, William Modi, Akinori Masuda, Masaaki Yamada, Joost J. Oppenheim, Kouji Matsushima, and Stephen J. O'Brien
Mammalian genome organization: an evolutionary view, S. J. O'Brien and H. N.J.E. Seuanez Womack
Barbara Kuhn, Stephen J. O'Brien
Interactive Influence of Infectious Disease and Genetic Diversity in Natural Populations, Stephen J. O'Brien and J. F. Evermann
The Human erg Gene Maps to Chromosome 21, Band q22: Relationship to the 8; 21 Translocation of Acute Myelogenous Leukemia, V. N. Rao, W. S. Modi, H. D. Drabkin, D. Patterson, Stephen J. O'Brien, T. S. Papas, and E. S. Reddy
The GLI-Kruppel Family of Human Genes, John M. Ruppert, Kenneth W. Kinzler, Albert J. Wong, Sandra H. Bigner, Fa-Ten Kao, Martha L. Law, Hector Seuanez, Stephen J. O'Brien, and Bert Vogelstein
Molecular Cloning and Chromosomal Localization of the Human T-Cell Receptor ζ Chain: Distinction from the Molecular CD3 Complex, Allan M. Weissman, Damon Hou, David G. Orloff, William S. Modi, Hector Seuanez, Stephen J. O'Brien, and Richard D. Klausner
Molecular Characterization and Genetic Mapping of Class I and Class II MHC Genes of the Domestic Cat, Naoya Yuhki and Stephen J. O'Brien
Submissions from 1987
A Novel Form of Human Polymorphism Involving the hDHFR-ψ1 Pseudogene Identifies Three RFLPs, Nicholas P. Anagnou, S. E. Antonarakis, Stephen J. O'Brien, and Arthur W. Nienhuis
Chromosomal Localization of the met Proto-Oncogene in the Mouse and Cat Genome, Michael Dean, Christine Kozak, Joan Robbins, Robert Callahan, Stephen J. O'Brien, and George F. Vande Woude
Molecular Analysis of Integrated Human Papillomavirus 16 Sequences in the Cervical Cancer Cell Line SiHa, Mostafa K. El Awady, Jeffrey B. Kaplan, Stephen J. O'Brien, and Robert D. Burk
A New Moderately Repetitive DNA Sequence Family of Novel Organization, Neal D. Epstein, S. Karlsson, Stephen J. O'Brien, William S. Modi, A. Moulton, and Arthur W. Nienhuis
A Molecular Phylogeny of the Hominoid Primates as Indicated by Two-Dimensional Protein Electrophoresis, David Goldman, P. Rathna Giri, and Stephen J. O'Brien
Isolation of a cDNA Clone for the Human Laminin-B1 Chain and its Gene Localization, Michael Jaye, William Modi, George A. Ricca, Robert Mudd, Inc-Ming Chiu, Stephen J. O'Brien, and William N. Drohan
The Human Myelin-Basic-Protein Gene: Chromosomal Localization and RFLP Analysis, John Kamholz, Richard Spielman, William Modi, Stephen J. O'Brien, and Robert Lazzarini
Partial Structure of the Human α2(IV) Collagen Chain and Chromosomal Localization of the Gene (COL4A2), Paul D. Killen, Clair A. Francomano, Yoshihiko Yamada, William Modi, and Stephen J. O'Brien
Identification of an Amplified, Highly Expressed Gene in a Human Glioma, Kenneth W. Kinzler, Sandra H. Bigner, Darrell D. Bigner, Jeffrey M. Trent, Martha L. Law, Stephen J. O'Brien, Albert J. Wong, and Bert Vogelstein
Report of the Committee on Comparative Mapping, P. A. Lalley, Stephen J. O'Brien, N. Creau-Goldberg, M. T. Davisson, T. H. Roderick, G. Echard, J. E. Womack, J. M. Graves, D. P. Doolittle, and J. N. Guidi
The Interleukin 3 Gene is Located on Human Chromosome 5 and is Deleted in Myeloid Leukemias with a Deletion of 5q, MIchelle M. LeBeau, Neal D. Epstein, Stephen J. O'Brien, Arthur W. Nienhuis, Yu-Chung Yang, Steven C. Clark, and Janet D. Rowley
Cytogenetic Methodologies for Gene Mapping and Comparative Analyses in Mammalian Cell Culture Systems, William Modi, William Nash, Anna C. Ferrari, and Stephen J. O'Brien
Analysis of Fluctuating Asymmetry in Cheetahs, William S. Modi, Robert K. Wayne, and Stephen J. O'Brien
A Comparative Chromosome Banding Analysis of the Ursidae and Their Relationship to Other Carnivores, William G. Nash and Stephen J. O'Brien
Biochemical genetic variation in geographic isolates of African and Asiatic lions., S. J. O'Brien
The Ancestry of the Giant Panda, Stephen J. O'Brien
Evidence for African Origins of Founders of the Asiatic Lion Species Survival Plan, Stephen J. O'Brien, P. Joslin, G. L. Smith III, R. Wolfe, N. Schaffer, E. Heath, J. Ott-Joslin, P. P. Rawal, K. K. Bhattacharjee, and Janice S. Martenson
The Future of the Giant Panda, Stephen J. O'Brien and John A. Knight
East African Cheetahs: Evidence for Two Population Bottlenecks?, Stephen J. O'Brien, David E. Wildt, Mitchell Bush, Timothy M. Caro, Clare Fitzgibbon, Issa Aggundey, and Richard E. Leakey
Chromosomal Evolution of the Canidae. II. Divergence from the Primitive Carnivore Karyotype, R. K. Wayne, W. G. Nash, and Stephen J. O'Brien
Chromosomal Evolution of the Canidae. I. Species with High Diploid Numbers, R. K. Wayne, W. G. Nash, and Stephen J. O'Brien
Allozyme Divergence Within the Canidae, Robert K. Wayne and Stephen J. O'Brien
Reproductive and Genetic Consequences of Founding Isolated Lion Populations, David E. Wildt, Mitchell Bush, K. L. Goodrowe, Craig Packer, A. E. Pusey, J. L. Brown, P. Joslin, and Stephen J. O'Brien
Similarity in Ejaculate-Endocrine Characteristics in Captive Versus Free-Ranging Cheetahs of Two Subspecies, David E. Wildt, Stephen J. O'Brien, J. G. Howard, T. M. Caro, M. E. Roelke, J. L. Brown, and Mitch E. Bush
Submissions from 1986
Chromosomal Mapping of Enzyme Loci in the Domestic Cat: GSR to C2, ADA and ITPA to A3, and LDHA-ACP2 to D1, E. J. Berman, W. G. Nash, H. N. Seuanez, and Stephen J. O'Brien
Comparative Genetic Mapping of Cellular rel Sequences in Man, Mouse, and the Domestic Cat, Elise Brownell, Christine Kozak, John R. Fowle III, William Modi, Nancy Rice, and Stephen J. O'Brien
Genetic Characterization of Human c-rel Sequences, Elise Brownell, Stephen J. O'Brien, William Nash, and Nancy Rice
Genetic Variation Within and Among Lion Tamarins, Lisa Forman, Devra G. Kleiman, R. Mitchell Bush, James M. Dietz, Jonathan D. Ballou, Lyndsay G. Phillips, Adelmar F. Coimbra-Filho, and Stephen J. O'Brien
Cloning, Characterization, Expression, and Chromosomal Localization of a Human Ferritin Heavy-Chain Gene, Matthias W. Hentze, Stephen Keim, Panos Papadopoulos, Stephen J. O'Brien, William Modi, Jim Drysdale, William J. Leonard, Joe B. Harford, and Richard D. Klausner
Human Endothelial Cell Growth Factor: Cloning, Nucleotide Sequence, and Chromosome Localization, Michael Jaye, Richard Howk, Wilson Burgess, George A. Ricca, Ing-Ming Chiu, Mark W. Ravera, Stephen J. O'Brien, William Modi, Thomas Maciag, and William N. Drohan
Molecular Genetics in the Domestic Cat and its Relatives, Stephen J. O'Brien
Chromosomal Mapping of Beta-Globin and Albino Loci in the Domestic Cat: a Conserved Mammalian Chromosome Group, Stephen J. O'Brien, M. E. Haskins, Cheryl Winkler, William G. Nash, and D. F. Patterson
Palaeontological and Molecular Views of Panda Phylogeny, Stephen J. O'Brien, William G. Nash, Raoul E. Benveniste, David E. Wildt, and Mitch E. Bush
The Cheetah in Genetic Peril, Stephen J. O'Brien, David E. Wildt, and Mitchell Bush
Molecular Evolution of ets Genes from Avians to Mammals and Their Cytogenetic Localization to Regions Involved in Leukemia, T. S. Papas, D. K. Watson, N. Sacchi, Stephen J. O'Brien, and R. Ascione
The Cellular ets Genes: Molecular Biology and Clinical Implications in Human Leukemias, T. S. Papas, D. K. Watson, N. Sacchi, Stephen J. O'Brien, and R. Ascione
Mechanism of met Oncogene Activation, Morag Park, Michael Dean, Colin S. Cooper, Martin Schmidt, Stephen J. O'Brien, Donald G. Blair, and George F. Vande Woude
Dynamic and Nonspecific Dispersal of Human T-Cell Leukemia/Lymphoma Virus Type-I Integration in Cultured Lymphoma Cells, Leonard J. Seigel, William G. Nash, Bernard J. Poiesz, Janet L. Moore, and Stephen J. O'Brien
Transactivation Induced by Human T-Lymphotropic Virus Type III (HTLV III) Maps to a Viral Sequence Encoding 58 Amino Acids and Lacks Tissue Specificity, Leonard J. Seigel, Lee Ratner, Steven F. Josephs, David Dersefi, Mark B. Feinberg, Gregory R. Reyes, Stephen J. O'Brien, and Flossie Wong-Staal
Amplification and Chromosomal Dispersion of Human Endogenous Retroviral Sequences, Paul E. Steele, Malcolm A. Martin, Arnold B. Rabson, Theodore Bryan, and Stephen J. O'Brien
Tetraploid Partial Hydatidiform Moles: Two Cases with a Triple Paternal Contribution and a 92,XXXY Karyotype, U. Surti, A. E. Szulman, K. Wagner, M. Leppert, and Stephen J. O'Brien
Conserved Chromosomal Positions of Dual Domains of the ets Protooncogene in Cats, Mice, and Humans, Dennis K. Watson, Mary J. McWilliams-Smith, Christine Kozak, Roger Reeves, John Gearheart, Michael F. Nunn, William Nash, John R. Fowle III, Peter Duesberg, Takis S. Papas, and Stephen J. O'Brien
Genetic Monitors of Zoo Populations: Morphological and Electrophoretic Assays, Robert K. Wayne, Lisa Forman, A. Newman, Janice M. Simonson, and Stephen J. O'Brien
Morphological Variability and Asymmetry in the Cheetah (Acinonyx jubatus), a Genetically Uniform Species, Robert K. Wayne, William Modi, and Stephen J. O'Brien
Empirical Demonstration That Structural Gene and Morphometric Variation of Mandible Traits are Uncoupled Between Mouse Strains, Robert K. Wayne and Stephen J. O'Brien
Developing Animal Model Systems for Embryo Technologies in Rare and Endangered Wildlife, David E. Wildt, M. C. Schiewe, P. M. Schmidt, K. L. Goodrowe, J. G. Howard, Lyndsay G. Phillips, Stephen J. O'Brien, and Mitch E. Bush
Submissions from 1985
Organization and Chromosomal Specificity of Autosomal Homologs of Human Y Chromosome Repeated DNA, Robert D. Burk, Paul Szabo, Stephen J. O'Brien, William G. Nash, Lohchung Yu, and Kirby D. Smith
A Molecular Phylogeny of the Felidae: Immunological Distance, Glen E. Collier and Stephen J. O'Brien
Twenty-Seven Protein Polymorphisms by Two-Dimensional Electrophoresis of Serum, Erythrocytes, and Fibroblasts in Two Pedigrees, David Goldman, Lynn R. Goldin, P. Rathnagiri, Stephen J. O'Brien, Janice A. Egeland, and Carl R. Merril
Biochemical Genetic Variation in Eight Endangered or Threatened Felid Species, A. Newman, Mitchell Bush, David E. Wildt, Dick Van Dam, Maarten Th. Frankenhuis, Lee Simmons, Lyndsay Phillips, and Stephen J. O'Brien
Expression of the Human C-Fms Proto-Oncogene in Hematopoietic Cells and its Deletion in the 5q− Syndrome, Arthur W. Nienhuis, H. Franklin Bunn, Patricia H. Turner, T. Venkat Gopal, William Nash, Stephen J. O'Brien, and Charles J. Sherr
A Molecular Solution to the Riddle of the Giant Panda's Phylogeny, Stephen J. O'Brien, William G. Nash, David E. Wildt, Mitchell Bush, and Raoul E. Benveniste
Genetic Basis for Species Vulnerability in the Cheetah, Stephen J. O'Brien, M. E. Roelke, L. Marker, A. Newman, Cheryl Winkler, D. G. Meltzer, L. Colly, J. F. Evermann, M. Bush, and David E. Wildt
Genetic Mapping of Endogenous RD-114 Retroviral Sequences of Domestic Cats, Roger H. Reeves, William G. Nash, and Stephen J. O'Brien
The ets Sequence from the Transforming Gene of Avian Erythroblastosis Virus, E26, has Unique Domains on Human Chromosomes 11 and 21: Both Loci are Transcriptionally Active, Dennis K. Watson, Mary J. McWilliams-Smith, M. F. Nunn, Peter Duesberg, Stephen J. O'Brien, and Takis S. Papas
Submissions from 1984
Chromosomal Organization of the Human Dihydrofolate Reductase Genes: Dispersion, Selective Amplification, and a Novel Form of Polymorphism, Nicholas P. Anagnou, Stephen J. O'Brien, Takashi Shimada, William G. Nash, Mann-Jy Chen, and Arthur W. Nienhuis
The Human Homologs of the raf (mil) Oncogene are Located on Human Chromosomes 3 and 4, Tom I. Bonner, Stephen J. O'Brien, William Nash, Ulf R. Rapp, Cynthia C. Morton, and Philip Leder
Isolation of HTLV-Transformed B-Lymphocyte Clone from a Patient with HTLV-Associated Adult T-Cell Leukaemia, Dan L. Longo, Edward P. Gelmann, Jeffrey Cossman, Rebecca A. Young, Robert C. Gallo, Stephen J. O'Brien, and Louis A. Matis
Giant Panda Paternity, Stephen J. O'Brien, David Goldman, John Knight, Harry D. Moore, David E. Wildt, Mitchell Bush, Richard J. Montali, and Devra Kleiman
ERV3, a Full-Length Human Endogenous Provirus: Chromosomal Localization and Evolutionary Relationships, Cathy O'Connell, Stephen J. O'Brien, William G. Nash, and Maurice Cohen
Molecular Genetic Characterization of the RD-114 Gene Family of Endogenous Feline Retroviral Sequences, Roger H. Reeves and Stephen J. O'Brien
Report of the Committee on Comparative Mapping, T. H. Roderick, P. A. Lalley, M. T. Davisson, Stephen J. O'Brien, J. E. Womack, N. Creau-Goldberg, G. Echard, and K. L. Moore
Gene for T-Cell Growth Factor: Location on Human Chromosome 4q and Feline Chromosome B1, Leonard J. Seigel, Mary E. Harper, Flossie Wong-Staal, Robert C. Gallo, William Nash, and Stephen J. O'Brien
Submissions from 1983
Murine Retroviral Restriction Genes Fv-4 and Akvr-1 are Alleles of a Single Locus, Stephen J. O'Brien, Eric J. Berman, John D. Estes, and Murray B. Gardner
Mapping of an Endogenous Retroviral Sequence to Human Chromosome 18, Stephen J. O'Brien, Tom I. Bonner, Maurice Cohen, Cathy O'Connell, and William Nash
Dispersion of the ras Family of Transforming Genes to Four Different Chromosomes in Man, Stephen J. O'Brien, William G. Nash, Jerome L. Goodwin, Douglas R. Lowy, and Esther H. Chang
Parallels of Genomic Organization and of Endogenous Retrovirus Organization in Cat and Man, Stephen J. O'Brien, Roger Reeves, Janice M. Simonson, Mary Eichelberger, and William G. Nash
On the Distribution and Characteristics of Isozyme Expression in Mycoplasma, Acholeplasma, and Ureaplasma Species, Stephen J. O'Brien, Janice M. Simonson, S. Razin, and Michael F. Barile
The Cheetah is Depauperate in Genetic Variation, Stephen J. O'Brien, David E. Wildt, David Goldman, Carl R. Merril, and Mitchell Bush
Clonal Variation of MCF-7 Breast Cancer Cells In Vitro and in Athymic Nude Mice, Katherine Seibert, Samir M. Shafie, Timothy J. Triche, Jacqueline J. Whang-Peng, Stephen J. O'Brien, Jeffrey H. Toney, Karen K. Huff, and Marc E. Lippman
Unique Seminal Quality in the South African Cheetah and a Comparative Evolution in the Domestic Cat, David E. Wildt, Mitch E. Bush, J. G. Howard, Stephen J. O'Brien, D. G. Meltzer, Ann van Dyk, H. Ebedes, and D. J. Brand
Submissions from 1982
Conserved Regions of Homologous G-Banded Chromosomes Between Orders in Mammalian Evolution: Carnivores and Primates, William G. Nash and Stephen J. O'Brien
Genetic analysis in the domestic cat as an animal model for inborn errors, cancer and evolution., S. J. O'Brien, W. G. Nash, C. A. Winkler, and R. H. Reeves
Evidence for the Horizontal Acquisition of Murine AKR Virogenes by Recent Horizontal Infection of the Germ Line, Stephen J. O'Brien, Janet L. Moore, Malcolm A. Martin, and James E. Womack
Genetic Mapping in Mammals: Chromosome Map of Domestic Cat, Stephen J. O'Brien and William G. Nash
Report of the Committee on Comparative Mapping. Oslo Conference (1981): Sixth International Workshop on Human Gene Mapping, P. L. Pearson, T. H. Roderick, M. T. Davisson, P. A. Lalley, and Stephen J. O'Brien
Dispermic origin and clinical outcome of three complete hydatidiform moles with 46,XY karyotype, U. Surti, A. E. Szulman, and S. O'Brien
Submissions from 1981
Contamination of Hodgkin's Disease Cell Cultures, Nancy L. Harris, David L. Gang, Steven C. Quay, Sibrand Poppema, Paul C. Zamecnik, Walter A. Nelson-Rees, and Stephen J. O'Brien
A cytogenetic comparison of the G-banded karyotypes of the domestic cat and man, W. G. Nash and S. J. O'Brien
Owl Monkey Cell Line, Stephen J. O'Brien
Analysis of Multiple Isoenzyme Expression Among Twenty-Two Species of Mycoplasma and Acholeplasma, Stephen J. O'Brien, Janice M. Simonson, Marion W. Grabowski, and Michael F. Barile
Submissions from 1980
Akvr-1, a Dominant Murine Leukemia Virus Restriction Gene, is Polymorphic in Leukemia-Prone Wild Mice, Murray B. Gardner, Suraiya Rasheed, BIjay K. Pal, John D. Estes, and Stephen J. O'Brien
Characteristics of HeLa Strains: Permanent vs. Variable Features, W. A. Nelson-Rees, L. Hunter, G. J. Darlington, and Stephen J. O'Brien
The Extent and Character of Biochemical Genetic Variation in the Domestic Cat, Stephen J. O'Brien
Correlative Genetic Variation in Natural Populations of Cats, Mice and Men, Stephen J. O'Brien, Mitchell H. Gail, and David L. Levin
A Molecular Approach to the Identification and Individualization of Human and Animal Cells in Culture: Isozyme and Allozyme Genetic Signatures, Stephen J. O'Brien, John E. Shannon, and Mitchell H. Gail
Genetic Diversity in Leukemia-Prone Feral House Mice Infected with Murine Leukemia Virus, Catherine Rice, Murray B. Gardner, and Stephen J. O'Brien
Genetic Variance of Laboratory Outbred Swiss Mice, M. Catherine Rice and Stephen J. O'Brien