Genetic Mapping in Mammals: Chromosome Map of Domestic Cat

Authors

• Stephen J. O'Brien, National Cancer Institute at FrederickFollow
• William G. Nash, National Cancer Institute at Frederick

ORCID

0000-0001-7353-8301

ResearcherID

N-1726-2015

Document Type

Article

Publication Title

Science

ISSN

0036-8075

Publication Date

4-16-1982

Abstract

A genetic map of 31 biochemical loci located on 17 feline syntenic (linkage) groups has been derived by somatic cell genetic analysis of cat-rodent hybrids. Most of these syntenic groups have been assigned to one of the 19 feline chromosomes. Comparative linkage analysis of the feline biochemical loci and homologous human loci revealed considerable conservation of linkage associations between the primates and the Felidae (order Carnivora). Many of these same linkage groups have not been conserved in the murine genome. The genetic and evolutionary implications of comparative mapping analysis among mammalian species are discussed.

DOI

10.1126/science.7063884

Volume

216

Issue

4543

First Page

257

Last Page

265

Comments

©1982 American Association for the Advancement of Science

NSUWorks Citation

O'Brien, Stephen J. and William G. Nash. 1982. "Genetic Mapping in Mammals: Chromosome Map of Domestic Cat." Science 216, (4543): 257-265. doi:10.1126/science.7063884.