Comparative Genetic Mapping of Cellular rel Sequences in Man, Mouse, and the Domestic Cat

Authors

• Elise Brownell, National Cancer Institute at Frederick
• Christine Kozak, National Institute of Allergy and Infectious Diseases
• John R. Fowle III, National Cancer Institute at Frederick; Environmental Protection Agency
• William Modi, National Cancer Institute at Frederick
• Nancy Rice, National Cancer Institute at Frederick
• Stephen J. O'Brien, National Cancer Institute at FrederickFollow

ORCID

0000-0001-7353-8301

ResearcherID

N-1726-2015

Document Type

Article

Publication Title

American Journal of Human Genetics

ISSN

0002-9297

Publication Date

8-1986

Abstract

We used in situ hybridization techniques to assign the human c-rel locus to the centromere-proximal portion of the short arm of chromosome 2 (2cent-2p13). We also determined the chromosomal location of c-rel sequences in the domestic cat and the laboratory mouse by using a human c-rel fragment to screen panels of rodent X cat and hamster X mouse somatic cell hybrid DNAs. The c-rel locus apparently maintains similar syntenic relationships with other known genetic markers in the human and cat, but displays different linkage relationships in the mouse.

Volume

39

Issue

2

First Page

194

Last Page

202

Comments

©1986 by the American Society of Human Genetics. All rights reserved.

Additional Comments

National Cancer Institute contract #: NO1-CO-23909

NSUWorks Citation

Brownell, Elise; Christine Kozak; John R. Fowle III; William Modi; Nancy Rice; and Stephen J. O'Brien. 1986. "Comparative Genetic Mapping of Cellular rel Sequences in Man, Mouse, and the Domestic Cat." American Journal of Human Genetics 39, (2): 194-202. https://nsuworks.nova.edu/cnso_bio_facarticles/381