Title

Dispermic origin and clinical outcome of three complete hydatidiform moles with 46,XY karyotype

Authors

U. Surti, University of Pittsburgh Medical Center, Magee-Womens Hospital
A. E. Szulman, University of Pittsburgh Medical Center, Magee-Womens Hospital
S. O'Brien, University of Pittsburgh Medical Center, Magee-Womens HospitalFollow

Document Type

Article

Publication Date

9-1-1982

Publication Title

American Journal of Obstetrics and Gynecology

Volume

144

Issue/No.

1

First Page

84

Last Page

87

Abstract

Three new cases of complete, classic hydatidiform mole with a 46,XY karyotype are described. They originated by dispermy as demonstrated by chromosome and enzyme analyses. Levels of human chorionic gonadotropin decreased to normal spontaneously within a short time, indicating a benign course in these three cases. Of a total of 18 cases reported to date, postoperative clinical information was available for 10 patients. Two of these 10 patients had a malignant course with lung metastases. It is of theoretical and clinical importance to establish the magnitude of the risk of malignancy for hydatidiform mole with a 46,XY karyotype. © 1982.

NSUWorks Citation

Surti, U.; A. E. Szulman; and S. O'Brien. 1982. "Dispermic origin and clinical outcome of three complete hydatidiform moles with 46,XY karyotype." American Journal of Obstetrics and Gynecology 144, (1): 84-87. doi:10.1016/0002-9378(82)90399-4.

DOI

10.1016/0002-9378(82)90399-4