Faculty Articles

Faculty Articles

 
A selection of journal publications from faculty in the College of Pharmacy at Nova Southeastern University.

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Submissions from 2015

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A Woman With Seventh Nerve Palsy: Presentation and Management, Syed A. A. Rizvi

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Antiproliferative activity of the isoindigo 5'-Br in HL-60 cells is mediated by apoptosis, dysregulation of mitochondrial functions and arresting cell cycle at G0/G1 phase., Ayman M Saleh, Mustafa M El-Abadelah, Mohammad Azhar Aziz, Mutasem O Taha, Amre Nasr, and Syed A A Rizvi

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Multifunctional Polymeric Micelles Co-loaded with Anti-Survivin siRNA and Paclitaxel Overcome Drug Resistance in an Animal Model of Ovarian Cancer., Giuseppina Salzano, Gemma Navarro, Malav Suchin Trivedi, Giuseppe De Rosa, and Vladimir P Torchilin

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Alcohol Use among Latino Migrant Workers in South Florida, Jesús Sánchez

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Nonstatin Therapies for Management of Dyslipidemia: A Review, Karen R. Sando and Michelle Knight

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Measuring the Implementation and Effects of a Coordinated Care Model Featuring Diabetes Self-management Education Within Four Patient-Centered Medical Homes., Charles E. Sepers, Stephen B. Fawcett, Ruth Lipman, Jerry Schultz, Vicki Colie-Akers, and Alexandra Perez Rivera

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Sulfasalazine in ionic liquid form with improved solubility and exposure, M. Shadid, G. Gurau, J. L. Shamshina, B.-C. Chuang, S. Hailu, E. Guan, S. K. Chowdury, J.-T. Wu, Syed A. A. Rizvi, R. J. Griffin, and R. D. Rogers

Improved immobilization of gelatin on a modified polyurethane urea, Shideh Shaneh, Fatemah Shokrolahi, Parvin Shokrollahi, Hamid Yeganeh, Ehsan Seyedjafari, Abdolreza Ardeshirylajimi, and Hamid Omidian

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Cobicistat: Review of a Pharmacokinetic Enhancer for HIV Infection., Elizabeth M. Sherman, Marylee V. Worley, Nathan R. Unger, Timothy P Gauthier, and Jason J. Schafer

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"That's True Love:" Lived Experiences of Puerto Rican Perinatally HIV-Infected Youth within Their Families' Context., Georgina Silva-Suarez, Elena Bastida, Silvia E. Rabionet, Consuelo Beck-Sagué, Irma Febo, and Carmen Zorrilla

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Anticoagulation With Dabigatran: When to Worry, Devada Singh-Franco

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Potential for Dipeptidyl Peptidase-4 Inhibitor and Sodium Glucose Cotransporter 2 Inhibitor Single-Pill Combinations., Devada Singh-Franco

Magnesium and Medications, Kimberly Stultz

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Epigenetic effects of casein-derived opioid peptides in SH-SY5Y human neuroblastoma cells, Malav Suchin Trivedi, Nathaniel Hodgson, Stephen J. Walker, Geert Trooskens, Vineeth Nair, and Richard Carlton Deth

Differential Interleukin-6 Protein and mRNA Expression Levels in Angiotensin II Treated Cultured Rat Astrocytes, Yugandhar Gowrisankar Vudhya and Michelle A Clark

Submissions from 2014

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The FDA Funding Crisis, Judith Alphonse, Sireesha Bellam, Marlene Fernandez, Anishka Gilbert, Lauren Roper, Antonia Zapantis, and Robert C. Speth

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Increased expression of angiotensin II type 2 receptors in the solitary-vagal complex blunts renovascular hypertension, Graziela Torres Blanch, André Henrique Freiria-Oliveira, Guilherme Fleury Speretta, Eduardo J. Carrera, Hongwei Li, Robert C. Speth, Eduardo Colombari, Colin Sumners, and Débora S. Colombari

What You Do in High School Matters: High School GPA, Educational Attainment, and Labor Market Earnings as a Young Adult, Michael T French, Jenny F. Homer, Ioana Popovici, and Philip K. Robins

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The ocular renin-angiotensin system: a therapeutic target for the treatment of ocular disease, Michael J. Giese and Robert C. Speth

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Alcohol-induced hypertension: Mechanism and prevention., Kazim Husain, Rais A. Ansari, and Leon Ferder

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Sex-specific T-cell regulation of angiotensin II-dependent hypertension, Hong Ji, Wei Zheng, Xiangjun Li, Jun Liu, Xie Wu, Monan Angela Zhang, Jason G. Umans, Meredith Hay, Robert C. Speth, Shannon E. Dunn, and Kathryn Sandberg

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Analysis of actively transcribed DNA repair using a transfection-based system, Jean Johanna Latimer

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Unscheduled DNA synthesis: the clinical and functional assay for global genomic DNA nucleotide excision repair, Jean Johanna Latimer and Crystal M. Kelly

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Regulation and Disregulation of Mammalian Nucleotide Excision Repair: A Pathway to Nongermline Breast Carcinogenesis, Jean Johanna Latimer, Vongai J. Majekwana, Yashira R. Pabón-Padín, Manasi R. Pimpley, and Stephen G. Grant

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Selective inhibition of angiotensin receptor signaling through Erk1/2 pathway by a novel peptide, Jun Liu, Gina L. Yosten, Hong Ji, Dan Zhang, Wei Zheng, Robert C. Speth, Willis K. Samson, and Kathryn Sandberg

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Review of Continuing Education and Published Literature Related to Women’s Health and Pharmacy, Cynthia Moreau and Debbie L. Wilson

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Edward Bliss Emerson: The Blazing Star of a Complex Constellation, Silvia E. Rabionet

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Qualitative Research by a Non-Hierarchical Team, José G. Rigau-Pérez, Silvia E. Rabionet, Annette B. Ramírez de Arellano, Wilfredo A. Géigel, Raúl Mayo-Santana, and Alma Simounet

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Properly timed exposure to central ANG II prevents behavioral sensitization and changes in angiotensin receptor expression., Jessica Santollo, Philip E Whalen, Robert Charles Speth, Stewart D Clark, and Derek Daniels

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Distribution of non-AT1, non-AT2 binding of 125I-sarcosine1, isoleucine8 angiotensin II in neurolysin knockout mouse brains, Robert C. Speth, Eduardo J. Carrera, Catalina Bretón, Andrea Linares, Luz Gonzalez-Reiley, Jamala D. Swindle, Kira L. Santos, Ines Schadock, Michael Bader, and Vardan T. Karamyan

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Acute repeated intracerebroventricular injections of angiotensin II reduce agonist and antagonist radioligand binding in the paraventricular nucleus of the hypothalamus and median preoptic nucleus in the rat brain, Robert C. Speth, Peter J. Vento, Eduardo J. Carrera, Luz Gonzalez-Reily, Andrea Linares, Kira Santos, Jamala D. Swindle, and Derek Daniels

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A role for impaired regulatory T cell function in adverse responses to aluminum adjuvant-containing vaccines in genetically susceptible individuals., Todd D Terhune and Richard Carlton Deth

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Atypical signaling and functional desensitization response of MAS receptor to peptide ligands, Kalyan C. Tirupula, Russell Desnoyer, Robert C. Speth, and Sadashiva S. Karnik

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Economic Evaluations of Clinical Pharmacy Services: 2006–2010, Daniel R. Touchette, Fred Doloresco, Katie J. Suda, Alexandra Perez Rivera, Stuart Turner, Yash Jalundhwala, Maria C. Tangonan, and James M. Hoffman

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Redox-based epigenetic status in drug addiction: a potential contributor to gene priming and a mechanistic rationale for metabolic intervention., Malav Suchin Trivedi and Richard Carlton Deth

Analysis of angiogenesis pathway-related gene expression impacted by MDM2 using PCR array, Thiagarajan Venkatesan, Corine Melanie Stinson, Sivanesan Dhandayuthapani, and Appu Rathinavelu

Submissions from 2013

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A Community-Based Pilot Study of a Diabetes Pharmacist Intervention in Latinos: Impact on Weight and Hemoglobin A1c, Ana M. Castejon, Jose Luis Calderón, Alexandra Perez Rivera, Claudia Millar, Jane McLaughlin-Middlekauff, Nisaratana Sangasubana, Goar Alvarez, Lillian Arce-Malave, Patrick Hardigan, and Silvia E. Rabionet

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Pancreatic angiotensin-converting enzyme 2 improves glycemia in angiotensin II-infused mice, Kavaljit H. Chhabra, Huijing Xia, Kim Brint Pedersen, Robert C. Speth, and Eric Lazartigues

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Brain RAS: Hypertension and Beyond, Marc de Gasparo, Robert C. Speth, Ovidiu C. Baltatu, and Patrick Vanderheyden

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Angiotensin type 1 receptor resistance to blockade in the opossum proximal tubule cell due to variations in the binding pocket, Ravi Nistala, Bradley T. Andresen, Lakshmi Pulakat, Alex Meuth, Catherine Sinak, Chirag Mandavia, Thomas Thekkumkara, Robert C. Speth, Adam Whaley-Connell, and James R. Sowers

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Immunohistochemical Localization of AT1a, AT1b, and AT2 Angiotensin II Receptor Subtypes in the Rat Adrenal, Pituitary, and Brain with a Perspective Commentary, Courtney Premer, Courtney Lamondin, Ann Mitzey, Robert C. Speth, and Mark S. Brownfield

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Epinephrine (adrenaline) absorption from new-generation, taste-masked sublingual tablets: a preclinical study, Ousama Rachid, Mutasem M Rawas-Qalaji, F Estelle R Simons, and Keith J Simons

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Long-term stability of epinephrine sublingual tablets for the potential first-aid treatment of anaphylaxis, Mutasem M Rawas-Qalaji, Ousama Rachid, F Estelle R Simons, and Keith J Simons

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The effects of para-chloromercuribenzoic acid and different oxidative and sulfhydryl agents on a novel, non-AT1, non-AT2 angiotensin binding site identified as neurolysin, Kira L. Santos, Megan A. Vento, John W. Wright, and Robert C. Speth

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Improvement in Surrogate Endpoints by a Multidisciplinary Team in a Mobile Clinic Serving a Low-Income, Immigrant Minority Population in South Florida, Devada Singh-Franco, Alexandra Perez Rivera, and William R. Wolowich

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Pharmacological characterization of a novel non-AT1, non-AT2 angiotensin binding site identified as neurolysin, Jamala D. Swindle, Kira L. Santos, and Robert C. Speth

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WNT10B/β-catenin signalling induces HMGA2 and proliferation in metastatic triple-negative breast cancer, Peter Wend, Stephanie Runke, Korinna Wend, Brenda Anchondo, Maria Yesayan, Meghan Jardon, Natalie Hardie, Christoph Loddenkemper, Ilya Ulasov, Maciej S. Lesniak, Rebecca Wolsky, Laurent A. Bentolila, Stephen G. Grant, David Elashoff, Stephan Lehr, Jean Johanna Latimer, Shikha Bose, Husain Sattar, Susan A. Krum, and Gustavo A. Miranda-Carboni

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Adenoviral and adeno-associated viral vectors-mediated neuronal gene transfer to cardiovascular control regions of the rat brain, Yanling Zhang, Yongxin Gao, Robert C. Speth, Nan Jiang, Yingying Mao, Colin Sumners, and Hongwei Li

Submissions from 2012

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Rapidly-disintegrating sublingual tablets of epinephrine: role of non-medicinal ingredients in formulation development, Ousama Rachid, Mutasem Rawas-Qalaji, F Estelle R Simons, and Keith J Simons

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Advances in ocular drug delivery, Mutasem Rawas-Qalaji and Cheryl-Ann Williams

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Identification of membrane-bound variant of metalloendopeptidase neurolysin (EC 3.4.24.16) as the non-angiotensin type 1 (non-AT1), non-AT2 angiotensin binding site, Naomi J. Wangler, Kira L. Santos, Ines Schadock, Fred K. Hagen, Emanuel Escher, Michael Bader, Robert C. Speth, and Vardan T. Karamyan

Submissions from 2011

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Comparison of Rate Control versus Rhythm Control for Management of Atrial Fibrillation in Patients with Coexisting Heart Failure: A Cost-Effectiveness Analysis, Alexandra Perez Rivera, Daniel R. Touchette, Robert J. DiDomenico, Thomas D. Stamos, and Surrey M. Walton

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How I Learned to Design and Conduct Semi-structured Interviews: An Ongoing and Continuous Journey, Silvia E. Rabionet

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Dissolution testing of sublingual tablets: a novel in vitro method, Ousama Rachid, Mutasem Rawas-Qalaji, F Estelle R Simons, and Keith J Simons

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The Effect of Pramlintide Acetate on Glycemic Control and Weight in Patients with Type 2 Diabetes Mellitus and in Obese Patients without Diabetes: A Systematic Review and Meta-Analysis, Devada Singh-Franco, Alexandra Perez Rivera, and C Harrington

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Identification of Hydroxysteroid (17β) dehydrogenase type 12 (HSD17B12) as a CD8+ T-cell-defined human tumor antigen of human carcinomas, Carmen Visus, Diasuke Ito, Rajiv Dhir, Miroslaw J. Szczepanski, Yoo Jung Chang, Jean Johanna Latimer, Stephen G. Grant, and Albert B DeLeo

Submissions from 2010

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AT₁ angiotensin II receptor and novel non-AT₁, non-AT₂ angiotensin II/III binding site in brainstem cardiovascular regulatory centers of the spontaneously hypertensive rat, Erick A. Bourassa, Xiefan Fang, Xia Li, Alan F. Sved, and Robert C. Speth

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Water deprivation increases angiotensin-converting enzyme but not AT(1) receptor expression in brainstem and paraventricular nucleus of the hypothalamus of the rat, Erick A. Bourassa and Robert C. Speth

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Anteroposterior distribution of AT(1) angiotensin receptors in caudal brainstem cardiovascular regulatory centers of the rat, Erick A. Bourassa, Alan F. Sved, and Robert C. Speth

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Brain-selective overexpression of human Angiotensin-converting enzyme type 2 attenuates neurogenic hypertension, Yumei Feng, Huijing Xia, Yanhui Cai, Carmen M. Halabi, Lenice K. Becker, Robson A. Santos, Robert C. Speth, Curt D. Sigmund, and Eric Lazartigues

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Angiotensin-converting enzyme 2: a new target for neurogenic hypertension, Yumei Feng, Huijing Xia, Robson A. Santos, Robert Speth, and Eric Lazartigues

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Preliminary biochemical characterization of the novel, non-AT1, non-AT2 angiotensin binding site from the rat brain, Vardan T. Karamyan, Jason Arsenault, Emanuel Escher, and Robert C. Speth

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Nucleotide excision repair deficiency is intrinsic in sporadic stage I breast cancer, Jean Johanna Latimer, Jennifer M. Johnson, Crystal M. Kelly, Tiffany D. Miles, Kelly A. Beaudry-Rodgers, Nancy A. Lalanne, Victor G. Vogel, Amal Kanbour-Shakir, Joseph L. Kelley, Ronald R. Johnson, and Stephen G Grant

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Design, synthesis, and docking studies of novel benzimidazoles for the treatment of metabolic syndrome, Cassia S. Mizuno, Amar G. Chittiboyina, Falgun H. Shah, Akshay Patny, Theodore W. Kurtz, Harrihar A. Pershadsingh, Robert C. Speth, Vardan T. Karamyan, Paulo B. Carvalho, and Mitchell A. Avery

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Neuronal differentiation of NG108-15 cells has impact on nitric oxide- and membrane (natriuretic peptide receptor-A) cyclic GMP-generating proteins, Dieter Müller, Karen J. Greenland, Robert C. Speth, and Ralf Middendorff

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Distribution of a novel binding site for angiotensins II and III in mouse tissues, Felicia M. Rabey, Vardan T. Karamyan, and Robert C. Speth

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An electronic tongue: evaluation of the masking efficacy of sweetening and/or flavoring agents on the bitter taste of epinephrine, Ousama Rachid, F Estelle R Simons, Mutasem Rawas-Qalaji, and Keith J Simons

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Permanently blocked stem cells derived from breast cancer cell lines, Gangadharan B Sajithlal, Kristi Rothermund, Fang Zhang, David J. Dabbs, Jean Johanna Latimer, Stephen G. Grant, and Edward V. Prochownik

Submissions from 2009

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Angiotensin modulation of rostral ventrolateral medulla (RVLM) in cardiovascular regulation, Erick A. Bourassa, Alan F. Sved, and Robert C. Speth

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Brain AT1 angiotensin receptor subtype binding: importance of peptidase inhibition for identification of angiotensin II as its endogenous ligand, Vardan T. Karamyan, Rama Gadepalli, John M. Rimoldi, and Robert C. Speth

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Expression of guanylyl cyclase (GC)-A and GC-B during brain development: evidence for a role of GC-B in perinatal neurogenesis, Dieter Müller, Balanes Hida, Gabriela Guidone, Robert C. Speth, Tatyana V. Michurina, Grigori Enikolopov, and Ralf Middendorff

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ACCP: Economic Evaluations of Clinical Pharmacy Services: 2001-2005, Alexandra Perez Rivera, Fred Doloresco, James M. Hoffman, Patrick D. Meek, Daniel R. Touchette, Lee C. Vermeulen, and Glen T. Schumock

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Long-term stability of epinephrine dispensed in unsealed syringes for the first-aid treatment of anaphylaxis, Mutasem Rawas-Qalaji, F Estelle R Simons, David Collins, and Keith J Simons

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Levocetirizine for the Treatment of Allergic Rhinitis and Chronic Idiopathic Urticaria in Adults and Children, Devada Singh-Franco, Hoytin Lee Ghin, Gisela I. Robles, Nancy Borja-Hart, and Alexandra Perez Rivera

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A life well-lived: Henry I. "Hank" Yamamura, Robert C. Speth

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Serotonin rising, Robert C. Speth

Submissions from 2008

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Cannabinoid ester constituents from high-potency Cannabis sativa, Safwat A. Ahmed, Samir A. Ross, Desmond Slade, Mohamed M. Radwan, Fazila Zulfiqar, Rae R. Matsumoto, Yan-Tong Xu, Eddy Viard, Robert C. Speth, Vardan T. Karamyan, and M A. ElSohly

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Impact of Treatment Guidelines on Clinical and Economic Outcomes of Acute Decompensated Heart Failure, Robert J. Didomenico, Alexandra Perez Rivera, Heather M. Schumann, Dee R. Fontana, George T. Kondos, and Glen T. Schumock

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Characterization of the brain-specific non-AT(1), non-AT(2) angiotensin binding site in the mouse, Vardan T. Karamyan, Florian Gembardt, Felicia M. Rabey, Thomas Walther, and Robert C. Speth

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Animal models of BMAA neurotoxicity: a critical review, Vardan T. Karamyan and Robert C. Speth

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Distribution of the non-AT1, non-AT2 angiotensin-binding site in the rat brain: preliminary characterization, Vardan T. Karamyan and Robert C. Speth

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Human brain contains a novel non-AT1, non-AT2 binding site for active angiotensin peptides, Vardan T. Karamyan, Craig A. Stockmeier, and Robert C. Speth

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Cell-type-specific level of DNA nucleotide excision repair in primary human mammary and ovarian epithelial cell cultures, Jean Johanna Latimer, Jennifer M. Johnson, Tiffany D. Miles, Jason M Dimsdale, Robert P. Edwards, Joseph L. Kelley, and Stephen G. Grant

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Brain angiotensin receptors and binding proteins, Robert C. Speth and Vardan T. Karamyan

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The significance of brain aminopeptidases in the regulation of the actions of angiotensin peptides in the brain, Robert C. Speth and Vardan T. Karamyan

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Sex differences in angiotensin signaling in bulbospinal neurons in the rat rostral ventrolateral medulla, Gang Wang, Teresa A. Milner, Robert C. Speth, Andrea C. Gore, Di Wu, Costantino Iadecola, and Joseph P. Pierce

Submissions from 2007

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Elevated levels of somatic mutation in a manifesting BRCA1 mutation carrier, Stephen G. Grant, Rubina Das, Christina M. Cerceo, Wendy S. Rubinstein, and Jean Johanna Latimer

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Placental insufficiency results in temporal alterations in the renin angiotensin system in male hypertensive growth restricted offspring, Daniela Grigore, Norma B. Ojeda, Elliot B. Robertson, Antoinette S. Dawson, Contrina A. Huffman, Erick A. Bourassa, Robert C. Speth, K Bridget Brosnihan, and Barbara T. Alexander

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Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7), Justin L. Grobe, Adam P. Mecca, Melissa Lingis, Vinayak Shenoy, Tonya A. Bolton, Juline M. Machado, Robert C. Speth, Mohan K. Raizada, and Michael J. Katovich

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Enzymatic pathways of the brain renin-angiotensin system: unsolved problems and continuing challenges, Vardan T. Karamyan and Robert C. Speth

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Identification of a novel non-AT1, non-AT2 angiotensin binding site in the rat brain, Vardan T. Karamyan and Robert C. Speth

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Central pressor actions of aminopeptidase-resistant angiotensin II analogs: challenging the angiotensin III hypothesis, Ranjita J. Kokje, Wendy L. Wilson, Travis E. Brown, Vardan T. Karamyan, John W. Wright, and Robert C. Speth

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Fast-disintegrating sublingual epinephrine tablets: effect of tablet dimensions on tablet characteristics., Mutasem M Rawas-Qalaji, F Estelle R Simons, and Keith J Simons

Submissions from 2006

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Association between biomarkers of environmental exposure and increased risk of breast cancer, M Donovan, T D. Miles, Jean Johanna Latimer, S Grant, E Talbott, A J. Sasco, and D L. Davis

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Homologous and lysophosphatidic acid-induced desensitization of the atrial natriuretic peptide receptor, guanylyl cyclase-A, in MA-10 leydig cells, Dieter Müller, Lourdes Cortes-Dericks, Lygia T. Budnik, Bärbel Brunswig-Spickenheier, Maria Pancratius, Robert C. Speth, Amal K. Mukhopadhyay, and Ralf Middendorff

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Fast-disintegrating sublingual tablets: effect of epinephrine load on tablet characteristics, Mutasem Rawas Qalaji, F Estelle R Simons, and Keith J Simons

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Epinephrine for the treatment of anaphylaxis: do all 40 mg sublingual epinephrine tablet formulations with similar in vitro characteristics have the same bioavailability?, Mutasem M Rawas-Qalaji, F Estelle R Simons, and Keith J Simons

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Sublingual epinephrine tablets versus intramuscular injection of epinephrine: dose equivalence for potential treatment of anaphylaxis, Mutasem M Rawas-Qalaji, F Estelle R Simons, and Keith J Simons

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Prospective screening study of 0.5 Tesla dedicated magnetic resonance imaging for the detection of breast cancer in young, high-risk women, Wendy S. Rubinstein, Jean J. Latimer, Jules H. Sumkin, Michelle Huerbin, Stephen G. Grant, and Victor G. Vogel

Submissions from 2005

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Basomedial hypothalamic injections of neuropeptide Y conjugated to saporin selectively disrupt hypothalamic controls of food intake, Kishor Bugarith, Thu T. Dinh, Ai-Jun Li, Robert C. Speth, and Sue Ritter