Objectives: The purpose of this study was to analyze and evaluate evidence supporting curcumin lowering the systemic inflammatory marker, CRP in humans. Methods: A systematic literature search was completed using PubMed and MEDLINE databases. Results: After inclusion and exclusion criteria, 9 studies were evaluated, and the percent change of CRP blood levels was calculated and analyzed. Results: The results for these studies show strong statistical significance for the C3 complex with Bioperine and nano curcumin. Bioactive curcumin exhibits a higher percent decrease of blood level CRP than trials using only curcumin or turmeric. Conclusion: Overall bioactive curcumin/ curcumin with Bioperine are alternative treatments for lowering the systemic inflammation marker, CRP.
Margret Danowski, Health Professions Librarian, Central Michigan University, for her assistance with the literature search.
Katakowski LA, Hewlings S. Bioactive Curcumin and its Effects on Lowering Systemic Inflammation as Measured by CRP: A Systematic Review. The Internet Journal of Allied Health Sciences and Practice. 2022 Jun 29;20(3), Article 10.