The Institute for Neuro Immune Medicine at Nova Southeastern University strives to advance knowledge and care for people with complex neuro-inflammatory illnesses through the integration of research, clinical care and education.

Current research focus at the Institute for Neuro Immune Medicine (INIM) includes Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Gulf War Illness (GWI). Investigators, clinicians and educators are committed to applying scientific advances to promote efficiency, enhance patient care and improve clinical utility. This advancement is done through clinical, laboratory, computational and integrative cardiovascular immunological research, all of which are conducted at the INIM by renowned researchers in their respective fields.

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Submissions from 1991

HIV 1 Disease Progression and Psychosocial Variables, Gail Ironson, J. Simoneau, Nancy G. Klimas, M. Antoni, A. LaPerriere, Neil Schneiderman, and Mary A. Fletcher

Submissions from 1990

Age and HIV‑1 Effects on Lymphocyte Phenotypes in Congenital Clotting Disorders (CCD) Patients, Mary A. Fletcher

Immunology of Chronic Fatigue Syndrome Seminario Sobre Psicoimmunologia, Mary A. Fletcher

Lymphocyte Phenotypes in HTLV Seropositive Blood Donors and Recipients, Mary A. Fletcher

Psychoimmunology of AIDS, Mary A. Fletcher

Psychoneurological Aspects of HIV‑1 Serostatus Notification, Mary A. Fletcher, M. Antoni, Nancy G. Klimas, A. LaPerriere, Gail Ironson, and N. Schneiderman

Psychosocial and Behavioral Factors associated with Perceived Risk of HIV‑1 Infection, Mary A. Fletcher, S. M. August, M. Antoni, A. LaPerriere, H. L. Baggett, P. O'Hearn, N. Schneiderman, and Gail Ironson

The Effects of Frequency of Relaxation Practice on Immune Markers in an HIV‑1 Infected High Risk Group, Mary A. Fletcher, H. L. Bagett, M. Antoni, S. August, A. LaPerriere, F. Ingram, and N. Schneiderman

Restaging of HIV‑1 Infection for Behavioral Medicine Research, Mary A. Fletcher, K. Goodkin, A. LaPerriere, N. Blaney, M. Morgan, C. Millon, and Szapocznik

High Anxiety Associated with Immune Suppression in Healthy Gay Males Regardless of HIV‑1 Antibody Status, Mary A. Fletcher, F. Ingram, M. Antoni, A. LaPerriere, P. O'Hearn, N. Schneiderman, and Gail Ironson

Cortisol Differences Between High and Low Depressed Men Before and After Receiving HIV‑1 Antibody Test Results, Mary A. Fletcher, F. Ingram, A. Friedamn, M. Antoni, A. LaPerriere, and N. Schneiderman

Lymphocyte Phenotypes in HIV‑1 Associated Neurological Disease, Mary A. Fletcher, Nancy G. Klimas, J. Berger, N. Stein, and C. Gamber

Hardiness, Coping and Immunity in HIV‑1 Infected Individuals, Mary A. Fletcher, M. S.W. Lutgendorf, S. August, and M. Antoni

Hormonal and Immunological Reactivity in HIV‑1 Seropositive and Seronegative Men, Mary A. Fletcher, N. Scheiderman, M. Antoni, and A. LaPerriere

Stress Management, Immunity and HIV‑1. Presented at the First Annual Meeting of the International Society of Behavioral Medicine, Mary A. Fletcher, N. Schneider, M. Antoni, and A. LaPerriere

Correlates of Depression Along Healthy Gay Males Awaiting Notification of HIV‑1 Antibody Test Results, Mary A. Fletcher, N. Schneider, M. Antoni, P. O'Hearn, N. Schneiderman, and Gail Ironson

Chronic Fatigue Syndrome ‑ Definition, Evaluation and Clinical Management, Nancy G. Klimas

Clinical Manifestations and Treatment and Prevention of AIDS, Nancy G. Klimas

Epidemiology, Clinical Manifestations and Therapy of HIV‑1 Infections, Nancy G. Klimas

Clinical vs Necropsy Findings in an AIDS Population, J. Pando and Nancy G. Klimas

Submissions from 1989

Behavior Modification Intervention Research in AIDS, Mary A. Fletcher

Immunophenotypes of Anti‑HTLV‑1 Positive (+) Blood Donors, Mary A. Fletcher

Psychoimmunology of AIDS: Stress and Exercise. symposium chaired by J. Gorman, Psychoimmunology Update, Mary A. Fletcher

Stress Management, Psychological and Immune, Mary A. Fletcher, M. Antoni, A. LaPerriere, N. Schneiderman, and Gail Ironson

Notification of HIV‑1 Antibody Status: Coping and Mood State in Healthy Gay Men, Mary A. Fletcher, S. August, Gail Ironson, M. Antoni, A. Laperrier, P. O'Hearn, D. Goldstein, F. Ingram, N. Schneiderman, and C. S. Craver

Frequency of Relaxation Practice, State Anxiety and Immune Markers in an HIV‑1 High Risk Group, Mary A. Fletcher, H. L. Baggett, M. Antoni, S. August, A. Laperrier, N. Schneiderman, and Gail Ironson

Serological and Cerebrospinal Fluid Parameters Related to Syphilis in HIV Asymptomatic Seropositives, Mary A. Fletcher, J. Berger, M. McCarthy, Nancy G. Klimas, E. Lo, and L. Pall

Neurological and Cognitive Correlates of T4 Lymphocyte Counts in Asymptomatic HIV Seropositive Adults, Mary A. Fletcher, J. Berger, M. McCarthy, T. Levin, E. DiDonna, Nancy G. Klimas, and L. Resnick

History of Syphilis as a Cofactor for the Expression of HIV Infection, Mary A. Fletcher, J. Berger, M. McCarthy, L. Resnick, Nancy G. Klimas, E. Lo, and L. Pall

T4 Lymphocyte Counts and Presence of Abnormalities on Neurological Examination in Asymptomatic HIV Seropositive Subjects, Mary A. Fletcher, J. Berger, M. McCarthy, L. Resnick, Nancy G. Klimas, E. Lo, and L. Pall

Cytokines in the Psychoimmunology of AIDS, Mary A. Fletcher, A. Friedman, Nancy G. Klimas, S. Spector, N. Schneiderman, and H. Friedman

Effects of Behavioral Intervention on Coping Behaviors in Healthy Gay Males at Risk for AIDS, Mary A. Fletcher, F. Ingram, A. LaPerrriere, S. August, P. O'Hearn, D. Goldstein, F. Ingram, and N. Schneiderman

Correlations of Immune Function with Mood and Coping Measures over Time in an AIDS Risk Group, Mary A. Fletcher, Gail Ironson, A. LaPerriere, S. August, P. O'Hearn, D. Goldstein, M. Antoni, and N. Schneiderman

Immunological and Psychological Predictors of Disease Progression in Gay males at Risk for AIDS, Mary A. Fletcher, Gail Ironson, A. LaPerriere, J. Simoneau, Nancy G. Klimas, and N. Schneiderman

Immunologic Measurements in Psychoimmunology, Mary A. Fletcher and Nancy G. Klimas

Immunophenotyping in Asymptomatic and Neurologically Symptomatic Anti‑HIV‑1 Positive and Anti‑HTLV‑1 Negative Men, Mary A. Fletcher, Nancy G. Klimas, J. Berger, and L. LaVoie

Cytokines and Immunoglobulins (Ig) in Cerebrospinal Fluid (CSF) of Anti‑HIV‑1 Positive, Anti‑HTLV‑1 Negative Asymptomatic Men, Mary A. Fletcher, Nancy G. Klimas, J. Berger, S. Spector, H. Friedman, and M. Ashman

Immunologic Abnormalities in Human Immunodeficiency Virus‑1 Negative (HIV‑) IV Drug Abusers (IVDA) on Methadone, Mary A. Fletcher, Nancy G. Klimas, N. Blaney, and R. Morgan

Immunological Parameters of Chronic Fatigue Syndrome (CFS), Mary A. Fletcher, Nancy G. Klimas, N. Blaney, and R. Morgan

Immunologic Abnormalities in Anti‑HIV‑1 negative (‑) and positive (+) IV drug Abusers (IVDA) on Methadone, Mary A. Fletcher, Nancy G. Klimas, N. Blaney, R. Morgan, and J. Simoneau

Immunologic Abnormalities of Seropositive and Seronegative Men, Mary A. Fletcher, Nancy G. Klimas, Gail Ironson, and A. LaPerriere

Immune Function in AIDS Risk Groups: Effects of Infection with Retroviruses and Polydrug (Including Alcohol) Use, Mary A. Fletcher, Nancy G. Klimas, R. Morgan, B. Page, D. Chitwood, N. Blaney, A. LaPerriere, and N. Schneiderman

Norepinephrine response and immune function in HIV Positive Subjects, Mary A. Fletcher, M. Kumar, R. Morgan, A. M. Kumar, J. Szapocznik, and C. Eisdorfer

Aerobic Exercise and Immune Function in an AIDS Risk Group, Mary A. Fletcher, A. LaPerrier, Gail Ironson, P. O'Hearn, P. Caralis, M. Antoni, F. Ingram, Nancy G. Klimas, L. Baggett, and N. Schneiderman

Aerobic Exercise Training as a Buffer of Anxiety and Depression in HIV Infected Individuals, Mary A. Fletcher, A. LaPerrier, Gail Ironson, P. O'Hearn, P. Caralis, M. Antoni, F. Ingram, Nancy G. Klimas, L. Baggett, and N. Schneiderman

Low Vitamin B6 Levels and Immune Dysfunction in HIV‑1 Infection, Mary A. Fletcher, E. Mantero-Atienza, R. Beach, F. Van Reil, R. Morgan, C. Eisdorfer, and M. Fordyce-Baum

Chronic Fatigue Syndrome: A Psychoimmunologic Disease, Nancy G. Klimas

Submissions from 1988

Immunomodulation of Patients with AIDS Related Complexes (ARC) During Therapy with Recombinant Interferon Gamma (IFNG), Mary A. Fletcher, G. A. Baron, M. A. Ashman, M. A. Fischl, and Nancy G. Klimas

Toward a Multivariate Biopsyschosocial Model of AIDS, Mary A. Fletcher, R. Beach, E. Mantero-Atienza, R. Morgan, N. Blaney, F. Wilkie, A. Guterman, G. Sfakianakis, R. Beach, G. Ramey, and C. Eisdorfer

Multiple Sclerosis‑like Illness with HIV Infection, Mary A. Fletcher, J. Berger, L. Resnick, S. Atherton, M. Norenberg, W. Sheremata, M. Coles, and J. Marcos

Mood State, Social Support and Immune Function in HIV‑ and HIV+ IV Drug Abusers, an AIDS Risk Group, Mary A. Fletcher, N. Blaney, Nancy G. Klimas, and R. Morgan

Immune Function and Aerobic Training as a Function of Anti HIV Status in Healthy Gay Males, Mary A. Fletcher, P. Caralis, A. Laperrier, Gail Ironson, Nancy G. Klimas, A. Perry, M. Ashman, and Neil Schneiderman

Seroprevalence and Risks of HIV Infections in Spouses of Persons Infected with HIV, Mary A. Fletcher, M. Fischl, T. Fayne, S. Flanagan, M. Ledan, R. Stevens, L. LaVoie, and E. Trapido

Phase I Study of Interferon Alpha and AZT in Patients with AIDS Related Kaposi’s Sarcoma, Mary A. Fletcher, M. Fischl, J. Reese, L. Dearman, L. Resnick, R. Argawal, and M. Myers

Evaluation of Immune Response During HIV Infection and AIDS: T Cell Subsets, Mary A. Fletcher, R. Gelman, J. V. Giorgi, P. Kidd, J. A. Koepke, A. Landay, S. Nusinoff, D. Lewis, J. Nicholson, H. Paxton, W. Rickman, D. Stites, and J. L. Fahey

A Behavioral Intervention Study in Anti‑HIV Positive and Negative Gay Men Presented at the 96th Annl Meeting of the American Psychological Society, Mary A. Fletcher, Gail Ironson, P. Caralis, A. LaPerriere, Nancy G. Klimas, P. O'Hearn, M. Antoni, and N. Schneiderman

News of Anti‑HIV Status and Immune Function in Healthy Gay Men, Mary A. Fletcher, Gail Ironson, P. O'Hearn, A. LaPerrier, M. Antoni, M. Ashman, and N. Schneiderman

Abnormal Lymphocyte Subsets and Natural Killer Cell Function in Anti‑HIV Negative Intravenous Drug Users on Methadone, Mary A. Fletcher, Nancy G. Klimas, N. Blaney, R. Morgan, and M. A. Ashman

Immune Abnormalities in Street Intravenous Drug Users, Mary A. Fletcher, Nancy G. Klimas, B. Page, D. Chitwood, and M. A. Ashman

Exercise and Immune Function in Healthy HIV Antibody Negative and Positive Gay Males, Mary A. Fletcher, A. LaPerrier, P. O'Hearn, Gail Ironson, P. Caralis, F. Ingram, A. Perry, Nancy G. Klimas, and N. Schneiderman

Retinol Binding Protein in Early HIV Infection, Mary A. Fletcher, E. Mantero-Atienza, R. Beach, R. Crass, R. Morgan, and M. A. Fordyce-Baum

Vitamin B12 Levels and Immune Function in Early HIV Infection, Mary A. Fletcher, E. Mantero-Atienza, R. Beach, R. Crass, R. Morgan, and M. A. Fordyce-Baum

Psychosocial Characterization of Chronic Fatigue Syndrome/Epstein‑Barr Virus Patients, Mary A. Fletcher, C. Millon, F. Salvato, F. Van Riel, N. Blaney, and Nancy G. Klimas

Anticipation and Reaction to Anti‑HIV Test Results: Effect on Immune Function in an AIDS Risk Group, Mary A. Fletcher, P. O'Hearn, F. Ingram, Gail Ironson, A. LaPerriere, Nancy G. Klimas, and N. Schneiderman

Immune Dysfunction Among Chronic Fatigue Syndrome (CFS) Patients with Clear Evidence for Epstein‑Barr Virus (EBV) Reactivation, Mary A. Fletcher, F. Salvato, M. Ashman, and Nancy G. Klimas

A Workshop on the Biopsychosocial Aspects of AIDS. 45th Annual Meeting of the American Psychosomatic Society, Mary A. Fletcher, G. F. Solomon, and L. Temoshok

Nutritional Status of Chronic Fatigue Syndrome (CFS)/ Epstein Barr Virus (EBV) Patients, Mary A. Fletcher, F. Van Reil, E. Mantero-Atienza, F. Salvato, R. Beach, Nancy G. Klimas, and M. Fordyce-Baum

The Association Between Visual spatial Skills and Immunologic Changes in Early HIV Infection, Mary A. Fletcher, F. Wilkie, R. Morgan, and C. Eisdorfer

The Psychoimmunology of HIV Infection in IV Drug Users, Nancy G. Klimas

Immunology Measures in Chronic Fatigue Syndrome, Nancy G. Klimas and Mary A. Fletcher

Submissions from 1987

Inter and Intra Personal Factors in the Recruitment and Retention of Subjects For an AIDS Intervention Research Study, S. Dodds, Mary A. Fletcher, P. O'Hearn, P. Cole, P. Caralis, and Nancy G. Klimas

Transfusion Safety Study Group: The Relationship of Antibody to HIV, Age, Sex and Treatment Status to Lymphocyte Subsets in Congenital Clotting Disorder (CCD) Patients, Mary A. Fletcher

Reduced Lymphocyte Cap Formation in Patients with AIDS and ARC. 3rd International Congress on AIDS, Mary A. Fletcher, G. Baron, L. Bouguignon, Nancy G. Klimas, M. A. Fischl, and G. B. Scott

Immune Parameters of Patients with AIDS/Kapaosi's Sarcoma During Human Lymphoblastoid Interferon Treatment, Mary A. Fletcher, G. Baron, Nancy G. Klimas, and M. A. Ashman

A Sialoglycopeptide from Bovine Erythrocytes which Interacts with the Paul‑Bunnell Antibody of Infectious Mononucleosis, Mary A. Fletcher and K. E. Caldwell

Studies on the Interaction of Mammalian Erythrocyte Membrane Sialoglycoproteins with the E‑Rosette Receptor of the Human T‑Lymphocyte, Mary A. Fletcher and K. E. Caldwell

Function and Aerobic Training as a Function of Anti‑HIV Status in Healthy Gay Males, Mary A. Fletcher, P. Caralis, A. LaPerriere, Gail Ironson, Nancy G. Klimas, A. Perry, N. Schneiderman, and M. Ashman

Inter‑ and Intra‑ Personal Factors in the Recruitment and Retention of Subjects For an AIDS Intervention Research Study. 3rd International Congress on AIDS, Mary A. Fletcher, S. Dodds, P. O'Hearn, P. Cole, and P. Caralis

The Biopsychosocial Research Center on AIDS: A Multidisciplinary Approach to the Investigation of the AIDS Disease, Mary A. Fletcher, C. Eisdorfer, G. Szapocznik, G. Scott, and Nancy G. Klimas

Human Immunodeficiency Virus (HIV) among Female Prostitutes in South Florida, Mary A. Fletcher, M. A. Fischl, G. A. Dickinson, and S. Flanagan

Decreased Natural Killer Cell Activity and Changes in T Lymphocyte Surface Markers in Patients with Chronic Epstein Barr Virus (EBV) Infection, Mary A. Fletcher, S. L. Tarsis, Nancy G. Klimas, G. S. Baron, and M. A. Ashman

Submissions from 1986

Abnormal Populations of Natural Killer Cells and Decreased Natural Cell Mediated Cytotoxicity in Patients with AIDS Related Complexes (ARC), Mary A. Fletcher and G. Baron

Inhibitory Effects of Serum from Patients with the Acquired Immunodeficiency Syndrome (AIDS) on in vitro Interferon Gamma (IFNG) and Interferon Alpha (INFA) Enhancement of Natural Cell‑Mediated Cytotoxicity (CYT), Mary A. Fletcher and G. Baron

Human T‑lymphotropic Virus Type III Infection Among Fema1e Prostitutes, Mary A. Fletcher, M. A. Fischl, G. M. Dickinson, and S. Flanagan

Heterosexual and Household Transmission of the Human T‑lymphotropic Virus Type II, Mary A. Fletcher, M. A. Fischl, G. M. Dickinson, G. B. Scott, Nancy G. Klimas, and W. Parks

Polyclonal B cell activation (PBA) and the Incidence of Antibody to HTLVIII/LAV (AB) in Groups at Risk for Acquired Immunodeficiency Syndrome (AIDS), Mary A. Fletcher and Nancy G. Klimas

Apparent False Positive ELISA Tests for HTLV/LAV Antibody (AB) and Polyclonal B cell Activation (PCBA) in Acquired Immunodeficiency Syndrome (AIDS) Risk Groups, Mary A. Fletcher, Nancy G. Klimas, E. Lian, and M. A. Fischl

Complement (C') Activation and Immune Complex (IC) Formation in Asymptomatic Women with Multiple Miscarriages, Mary A. Fletcher, Nancy G. Klimas, and M. Lubs

Submissions from 1985

Decreased Natural Cell Mediated Cytotoxicity (NCC) to Cell‑Line K562 per Leu 11 Positive Cells in Acquired Immunodeficiency Syndrome (AIDS), Mary A. Fletcher, G. A. Baron, Nancy G. Klimas, and M. A. Fischl

Natural Cell Mediated Cytotoxicity (NCC) to Cell Line K562 per Leu 11 Positive Cell is Decreased in the Acquired Immunodeficiency Syndrome, Mary A. Fletcher, G. A. Baron, Nancy G. Klimas, and M. A. Fischl

Use of Danozol in Autoimmune Thrombocytopenia Associated with the Acquired Immunodeficiency Syndrome, Mary A. Fletcher, M. A. Fischl, Y. S. Ahn, Nancy G. Klimas, and W. J. Harrington

Evaluation of Household Contacts of Adult Patients with the Acquired Immunodeficiency Syndrome, Mary A. Fletcher, M. A. Fischl, G. M. Dickinson, G. Scott, Nancy G. Klimas, and W. Parke

Human Lymphoblastoid Interferon Treatment of Kaposi's Sarcoma in Association with the Acquired Immunodeficiency Syndrome, Mary A. Fletcher, M. A. Fischl, E. Gorowski, G. Wang, and S. Lucas

Humoral Immune Abnormalities in Two South Florida Acquired Immunodeficiency Syndrome Risk Groups, Mary A. Fletcher, Nancy G. Klimas, O. Torres, G. Silveira, and M. A. Fischl

Mothers of Infants with the Acquired Immunodeficiency Syndrome (AIDS : Outcome of Subsequent Pregnancies, Mary A. Fletcher, G. B. Scott, M. A. Fischl, Nancy G. Klimas, G. Dickinson, and W. Parks

Submissions from 1984

Human ‑lymphoblastoid Interferon in the Treatment of Kaposi's Sarcoma, Internatl, Mary A. Fletcher, M. A. Fischl, Nancy G. Klimas, G. Wang, J. A. Georgiades, and T. Spira

Elevation of "Forssman‑like'' Antibody in AIDS, Mary A. Fletcher and Nancy G. Klimas

Submissions from 1983

A Low Molecular Weight Natural Plant Product That Breaks Down Microtubules in vivo and Prevents Tubulin Polymerization in vitro, Mary A. Fletcher, L. Y. Bourguiognon, K. E. Caldwell, D. Lehotay, and R. W. Rubin

N‑terminal Pyroglutamyl Residue‑ Part Of The Receptor For Paul‑Bunnell Antibody of Some Membrane‑Derived Sialoglycoproteins, Mary A. Fletcher and K. E. Caldwell

An Inhibitor of Tubulin Polymerization From Momordia charantia var abbreviata, Mary A. Fletcher, K. E. Caldwell, P. Kozlovskis, A. J. Claflin, and R. W. Rubin