The Institute for Neuro Immune Medicine at Nova Southeastern University strives to advance knowledge and care for people with complex neuro-inflammatory illnesses through the integration of research, clinical care and education.
Current research focus at the Institute for Neuro Immune Medicine (INIM) includes Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Gulf War Illness (GWI). Investigators, clinicians and educators are committed to applying scientific advances to promote efficiency, enhance patient care and improve clinical utility. This advancement is done through clinical, laboratory, computational and integrative cardiovascular immunological research, all of which are conducted at the INIM by renowned researchers in their respective fields.
Submissions from 1999
Flow Cytometric Analysis of Natural Killer Cell Perforin Content Correlates with Lytic Potential Clinical Applications of Cytometry, Mary A. Fletcher and K. Maher
Associations Between Viral Load, Natural Killer Cell (CD56+CD3-) Number, and State Anxiety among HIV Seropositive Men, Mary A. Fletcher, K. Maher, D. Cruess, M. Antoni, N. Schneiderman, and Nancy G. Klimas
Enhancing adherence to combination antiretroviral therapy in non-adherent HIV+ men, Nancy G. Klimas, R. Malow, F. J. Penedo, D. Jones, C. Maggio, J. Triplett, and Nancy G. Klimas
Submissions from 1998
Markers of immune progression in HIV, Mary A. Fletcher
Social support buffers PTSD symptoms and HHV-6 antibody titers in HIV+ gay men following hurricane Andrew, Mary A. Fletcher, D. Dixon, M. Antoni, K. Kilbourne, S. Wagner, and N. Schneiderman
Patterns of Immune Reconstitution in HIV-1 Infection Following Highly Active Anti-Retro-viral Therapy, Mary A. Fletcher, K. Maher, Nancy G. Klimas, G. Dickinson, J. Triplett, C. Maggio, and R. Valenzuela
Highly active anti-retroviral therapy: implications for adherence and immunomodulatory interventions, Nancy G. Klimas
Submissions from 1997
Cytokine patterns in chronic fatigue syndrome, Mary A. Fletcher
Non-compliant exercise decreases CD4+ cells in early symptomatic HIV infection, Mary A. Fletcher, A. LaPerriere, A. Goldstein, Nancy G. Klimas, Gail Ironson, P. Majors, G. Maik, C. Talluto, and N. Schneiderman
The Effect of highly active anti-retroviral therapy on viral load and the immune system in human immunodeficiency virus (HIV) iInfection, Mary A. Fletcher, K. Maher, Nancy G. Klimas, G. Dickinson, J. Triplett, C. Maggio, V. Cohen, and R. Valenzuela
T Lymphocyte Subsets and Highly Active Anti-Retroviral Therapy (HAART) of Human Immunodeficiency Virus (HIV) Infection, Mary A. Fletcher, K. Maher, Nancy G. Klimas, G. Dickinson, J. Triplett, C. Maggio, and R. Valenzuela
Effect of acute exercise on lymphocyte enumeration in HIV+ African-American women, Mary A. Fletcher, G. Mail-Rachline, A. LaPerriere, A. Perry, Nancy G. Klimas, C. Talluto, A. Goldstein, J. Junco, and Gail Ironson
Analysis of hemodialysis by RT/PCR for HIV after accidental splash of a dialysis provider, Mary A. Fletcher, C. Ortiz-Butcher, J. P. Pennell, J. Walling, and B. Zjacic
Update on anti-retroviral therapy in HIV, Nancy G. Klimas
Submissions from 1996
Cytokine abnormalities in CFS. Clinical Immunology Society, Mary A. Fletcher
Evaluation of mandated versus laboratory selected reagents for multicolor flow cytometry in multicenter clinical trials, Mary A. Fletcher
A Bereavement Support Group is Associated with increased Proliferation to PHA in HIV-1+ and HIV-1- Gay Men, Mary A. Fletcher, K. Goodkin, R. Tuttle, D. Feaster, N. T. Blaney, D. Asthana, and K. Maher
Stressor-induced immune response patterning in HIV-1 seropositive and seronegative individuals, Mary A. Fletcher, B. Hurwitz, M. Antoni, M. Kumar, J. A. Graves, J. R. Milanovich, S. Motivala, and N. Schneiderman
Patterns of proinflamatory and type 2 cytokines in CFS, Mary A. Fletcher, Nancy G. Klimas, and R. Patarca
Lymphocyte Phenotypes of Cord Blood From Healthy Infants, Mary A. Fletcher, K. Maher, Jin XQ, E. Nunez, G. Godoy, J. Infantis-Potter, and M. O'Sullivan
Submissions from 1995
Dysregulated cytokine patterns in CFS, Mary A. Fletcher
Multisite Clinical Trial of the TRAx CD4 assay. presented at the 2nd National Conference on CD4 Lymphocyte Phenotyping, Mary A. Fletcher
Update on the clinical laboratory immunology of HIV disease, Mary A. Fletcher
Behavioral, postural and reflex challenges reveal cardiovascular abnormalities in the progression of HIV infection, Mary A. Fletcher, B. E. Hurwitz, M. Antoni, Nancy G. Klimas, B. S. Steffen, L. Fillion, C. Leitten, and N. Schneiderman
Weight training and natural killer cell activity in the elderly, Mary A. Fletcher, A. LaPerriere, J. Signoreli, D. Flipse, F. Perna, and A. Perry
CD69 expression following in vitro stimulation with PHA on CD4 and CD8 cells from HIV-infected and normal control subjects, Mary A. Fletcher, K. Maher, D. Ashthana, and Nancy G. Klimas
CD69 on CD4 and CD8 Cells From HIV-1 infected Donors Clinical Applications of Cytometry, Mary A. Fletcher, K. Maher, D. Ashthana, R. Patarca, and Nancy G. Klimas
Immunological Correlates Among Children With Perinatally- Acquired Human Immunodeficiency Type-1 Virus Infection Association of Medical Laboratory Immunologists, Mary A. Fletcher, K. Maher, R. Patarca, C. Hutto, G. B. Scott, N. Martin, and Nancy G. Klimas
Immunologic attributes of HIV infected children who are slow progressors. presented at American Medical Laboratory immunology Association, Mary A. Fletcher, K. Maher, R. Patarca, J. Walling, D. Sandler, Nancy G. Klimas, G. Scott, and C. Hutto
CD8 T cell immunotherapy in AIDS: Lessons learned at the cellular and molecular biology levels, Mary A. Fletcher, R. Patarca, and Nancy G. Klimas
CD8 T cell-associated cytokine gene expression programs in AIDS, Mary A. Fletcher, R. Patarca, Nancy G. Klimas, J. Walling, X.S Yue, M. Garcia, and H. Pons
Submissions from 1994
The effect of perceived competence and responsiveness of the environment on psychological and physical health in HIV+ men following Hurricane Andrew. physiological and psychological impact of Hurricane Andrew on an HIV positive population as compared to other stressed populations, Mary A. Fletcher, C. Benight, M. Antoni, K. Kilbourne, and N. Schneiderman
Social provisions, optimism and distress levels in HIV+ men dealing with the aftermath of Hurricane Andrew, Mary A. Fletcher, N. Costello, K. Kilbourne, M. Antoni, Gail Ironson, and N. Schneiderman
The impact of Hurricane Andrew on HIV+ gay men: Anxiety, depression, coping and social support relationships to the disease progression marker, neopterin, Mary A. Fletcher, N. L. Costello, K. Kilbourne, M. Antoni, Gail Ironson, A. Baum, and N. Schneiderman
A bereavement support group intervention decreases psychological stress in HIV-1 infected homosexual men, Mary A. Fletcher, K. Goodkin, N. Blaney, D. Feaster, J. Burkhalter, B. Leeds, and R. Tuttle
Bereavement, depressed mood, and immunologic parameters in HIV+ men, Mary A. Fletcher, K. Goodkin, R. Tuttle, G. Molina, D. Feaster, N. Blaney, and T. Baldewitz
Correlates of distress and immune function in the aftermath of Hurricane Andrew, Mary A. Fletcher, Gail Ironson, C. Wynings, D. Greenwood, K. Burnett, C. Carver, C. Benight, M. Rodriquez, and N. Schneiderman
How are coping strategies that people use to handle major challenges related to their immune and neuroendocrine responses?, Mary A. Fletcher, K. Kilbourne, N. Costello, M. Antoni, Gail Ironson, A. Baum, and N. Schneiderman
The physiological and psychological impact of Hurricane Andrew on an HIV positive population as compared to other stressed populations, Mary A. Fletcher, K. Kilbourne, N. Costello, M. Antoni, Gail Ironson, and N. Schneiderman
Immunologic aspects of chronic fatigue syndrome. Presented at the American Psychosomatic Society, Mary A. Fletcher and Nancy G. Klimas
Lymphocyte transfusions to patients with AIDS, Mary A. Fletcher, J. T. Lane, M. Uribe, Nancy G. Klimas, R. Keller, F. Tomaka, B. Giannetti, P. Gamatos, and W. Reiter
Impact of avoidant thoughts on immune functioning in symptomatic HIV positive men, Mary A. Fletcher, S. Lutgendorf, M. Antoi, Gail Ironson, K. Starr, Nancy G. Klimas, M. Kumar, K. Cleven, F. Penedo, and N. Schneiderman
Neuroendocrine and immune effects of a psychosocial intervention in symptomatic HIV seropositive gay men, Mary A. Fletcher, S. Lutgendorf, M. Antoni, Gail Ironson, Nancy G. Klimas, M. Kumar, and N. Schneiderman
Cytokine patterns in chronic fatigue syndrome, Mary A. Fletcher, R. Patarca, H. Pons, M. Garcia, and Nancy G. Klimas
Submissions from 1993
Characterization of Ex Vivo Expanded CD8 T Cells, Mary A. Fletcher
Nutritional Abnormalities in Intravenous Drug Users (IVDUs): Impact of HIV-1 Status, Mary A. Fletcher, M. Baum, G. Shor-Pazner, J. Quesada, N. Cure, and J. Page
Cholesterol Level as an Indicator of HIV-1 Disease Progression, Mary A. Fletcher, P. Bonvehi, G. Shor-Posner, Y. Lu, and M. Baum
Possible Mechanisms of Elevated IgE in HIV-1 Disease, Mary A. Fletcher, M. Burbano-Miquez, and J. Moreno
Psychosocial Variables Predict Long Term Changes in Psychological Distress and Laboratory Progression Markers, Mary A. Fletcher, K. Goodkin, N. Blaney, D. Feaster, Nancy G. Klimas, and M. Baum
Baseline CD8 Counts as a Predictor of Survival in Patients with HIV-Associated Lymphoma Undergoing Chemotherapy, Mary A. Fletcher, W. Harrington, L. Cacral, R. Patarca, S. Lai, T. Venet, and Nancy G. Klimas
Evaluation of psychosocial, immune and endocrine impact of Hurricane Andrew in a Community Sample, Mary A. Fletcher, Gail Ironson, M. Antoni, D. Greenwood, Nancy G. Klimas, A. Baum, and N. Schneiderman
Immunologic Impact of Hurricane Andrew on Immune Markers in Individuals with HIV-1 Infection, Mary A. Fletcher, Nancy G. Klimas, and M. Antoni
Immunologic Impact of Hurricane Andrew on Immune Markers in Individuals with Chronic Fatigue Syndrome, Mary A. Fletcher, Nancy G. Klimas, M. Antoni, and S. Lutgendorf
Response of Kaposi's Sarcoma (KS) to Autologous CD8 cells, Expanded and Activated Ex Vivo and Reinfused with IL-2, Mary A. Fletcher, Nancy G. Klimas, J. Walling, V. Pardo, T. Ocarma, and J. Kremer
Cognitive Difficulties Correlate with Immune Function in Chronic Fatigue Syndrome, Mary A. Fletcher, S. Lutgendorf, Nancy G. Klimas, and M. Antoni
Low Affinity Receptor, (FceR) in T Cells, is Associated with IgE Production by Peripheral Blood Lymphocytes (PBL) in HIV+ Patients, Mary A. Fletcher, M. Miquez-Burbano, M. Baum, J. Moreno, X. Jin, and G. Shor-Posner
Possibilities of Autologous CD8 Cell Therapy In HIV Disease. Pediatric Immunology Working Group, Mary A. Fletcher, R. Patarca, and Nancy G. Klimas
Elevated IgE in Relationship to Plasma Vitamin E Levels in Early HIV-1 Disease. IXth Intl. Conf. on AIDS, Mary A. Fletcher, G. Shor-Posner, M. Miguez-Burbano, E. Mantero-Atienza, and M. Baum
Clinical Use of Ex Vivo Expanded CD8 T Cells in AIDS, Nancy G. Klimas
Submissions from 1992
Human Immunodeficiency virus (HIV) infection among patients of a dentist with AIDS, G. M. Dickinson, A. L. Bisno, R. Morhart, Nancy G. Klimas, and J. Laracuente
Elevated IgA Levels as an Early Indicator of HIV‑1 Infection in Columbians, Mary A. Fletcher, C. Allarriacin, R. Patarca, G. Martinez, J. Palacio, and E. Barbosa
Cognitive Appraisals, Coping Strategies Predict CFS Disturbances, Mary A. Fletcher, M. Antoni, A. Brickman, A. Imia-Fins, Nancy G. Klimas, S. Lutgendirf, Gail Ironson, R. Quillan, M. J. Miquez, F. Van Reil, R. Morgan, and Roberto Patarca
Behavioral Interventions Modulate IgG Antibody Titers to ECA‑VCA and HHV‑6 in HIV+ and HIV‑ Gay Men, Mary A. Fletcher, M. Antoni, B. Esterling, N. Schneiderman, A. LaPerriere, Gail Ironson, and Nancy G. Klimas
Soluble Immune Mediator Profiles in Cerebrospinal Fluids from HIV‑1 Infected Individuals with Different Neuropathologies, Mary A. Fletcher, R. Garcia-Morales, R. Patarca, C. Albarricin, Nancy G. Klimas, C. Gamber, and J. Berger
Correlation of DR4 and DQ1 with Immunologic Defects in CFS, Mary A. Fletcher, R. Keller, F. Van Reil, J. Maislis, J. Lane, W. Reiter, and Nancy G. Klimas
Phase 1 Trial of Adoptive Therapy with Purified CD8 Cells in HIV Infection, Mary A. Fletcher, Nancy G. Klimas, J. Walling, R. Garcia-Morales, R. Patarca, D. Moody, and T. Okarma
Adoptive Therapy with Purified CD8 Cells in HIV Infection, Mary A. Fletcher, Nancy G. Klimas, J. Walling, R. Patarca, C. Alberricin, V. Mayer, R. Garcia-Morales, C. Gamber, D. Moody, and T. Okama
Substance Abuse, NK Cells and Immune Function, Mary A. Fletcher, R. Morgan, and Nancy G. Klimas
Changes in the Expression Patterns of soluble Immune Mediator in Association with CD8+ T Cell Activation in CFS, Mary A. Fletcher, R. Patarca, Nancy G. Klimas, S. Lutgendorf, C. Albarracin, R. Garcia-Horales, F. van Reil, and M. Antoni
Autologous Cytotoxic T cell Activation, Expansion and Reinfusion with IL2 r in HIV Disease, Nancy G. Klimas
Submissions from 1991
Chronic Fatigue Syndrome, EBV and Stress, Mary A. Fletcher
Co‑infection with HIV‑1 and HTLV; Effect on Lymphocyte Phenotype, Mary A. Fletcher
Lymphocyte Phenotypes of HTLV‑1 and HTLV‑II Blood Donors, Mary A. Fletcher
Street IVDU: Immune function and HIV and HTLV infections, Mary A. Fletcher
Update on Clinical Laboratory Findings in HIV‑1 Infection, Mary A. Fletcher
Stress Management Intervention Buffers Distress Responses and Elevates Immunologic Markers Following Notification of HIV‑1 Seropositivity, Mary A. Fletcher, M. Antoni, H. Baggett, S. August, A. LaPerriere, Gail Ironson, Nancy G. Klimas, and N. Schneiderman
Immunological and Neuroendocrine Responsivity to Challenge in HIV‑infected Men, Mary A. Fletcher, M. Antoni, M. Rodriquez, K. Starr, M. Gellman, M. Kumar, S. Lutgendorf, C. Massie, Gail Ironson, A LaPerriere, and Neil Schneiderman
Predictors of Change in Immune Function: Longitudinal Analysis of Nutritional and Immune Status in Early HIV‑1 Infection, Mary A. Fletcher, M. K. Baum, R. Beach, E. Matero-Atienza, B. Rosner, C. Eisdorfer, and G. Shor-Posner
Effect of Zinc Normalization on Immunological Function in Early HIV‑1 Infection, Mary A. Fletcher, R. Beach, C. Cabrejos, E. Matero-Atienza, A. Basit, G. Shor-Posner, J. Chang, and M. K. Baum
Phenotype of CD8 Lymphocytes from HIV‑1 Infected Persons after Isolation and Ex‑Vivo Expansion, Mary A. Fletcher, R. T. Garcia-Morales, Nancy G. Klimas, J. Walling, R. Patarca, and D. Moody
Bereavement is Associated with Changes in Cellular Immune Function in Asymptomatic HIV‑1 Seropositive Gay men, Mary A. Fletcher, K. Goodkin, N. Blaney, D. Feaster, M. Baum, J. Szapocznik, and C. Eisdorfer
Plasma Cortisol Levels and Psychosocial Correlates of Depression Among Gay Men Before and After Receiving HIV‑1 Antibody Test Results, Mary A. Fletcher, F. Ingram, M. Antoni, A. LaPerriere, A. Friedman, P. O'Hearn, and N. Schneiderman
Blunted In Vitro Response to Catecholamines in HIV‑1 Seropositive Gay Men, Mary A. Fletcher, Gail Ironson, D. Hopper, M. Antoni, M. Kumar, A. LaPerriere, Nancy G. Klimas, and N. Schneiderman
Psychosocial Predictors of Disease Progress in HIV‑1 Infected Gay Men. Presented at the 99th Annual Meeting of the Amer, Mary A. Fletcher, Gail Ironson, J. Simoneau, A. Freidman, K. Starr, M. Antoni, A. LaPerriere, and N. Schneiderman
HIV‑1 Disease Progression and Psychosocial Variables, Mary A. Fletcher, Gail Ironson, J. Simoneau, Nancy G. Klimas, M. Antoni, A. LaPerriere, and N. Schneiderman
Relationship of HIV‑1 Disease Progression to Psychosocial Factors in Gay Men. 7th Internatl, Mary A. Fletcher, Nancy G. Klimas, Gail Ironson, J. Simoneau, A. Freidman, M. Antoni, and N. Schneiderman
No Serologic Evidence for HTLV‑I or II in Chronic Fatigue Syndrome, Mary A. Fletcher, Nancy G. Klimas, and H. Lee
Cytokine and other Soluble Marker Abnormalities in Chronic Fatigue Syndrome, Mary A. Fletcher, Nancy G. Klimas, and R. Patarca
Cytokines in Chronic Fatigue Syndrome, Mary A. Fletcher, Nancy G. Klimas, R. Patarca, W. King, and R. Gamble
Cognitive Processing and HIV‑1 Seropositivity Notification: Affective Sequela. Presented at the 12th Annl, Mary A. Fletcher, S. Lutgendorf, M. Antoni, A. LaPerriere, H. L. Baggett, K. Starr, and N. Schneiderman
Hardiness Affect and Immunity in HIV‑1 Infected Individuals. Presented at the 12th Annl. Meeting of the Soc, Mary A. Fletcher, S. Lutgendorf, S. August, M. Antoni, A. LaPerriere, and N. Schneiderman
Seleium Status and Immune Function in Early HIV‑1 Infection. 7th International Conference on AIDS, Mary A. Fletcher, E. Matero-Atienza, M. C. Sotomayor, G. Shor-Posner, R. Beach, A. Basit, C. Cabrejos, and M. K. Baum
Street IVDU: Immune function and HIV and HTLV infections, Mary A. Fletcher, J. B. Page, R. Morgan, and Nancy G. Klimas
Cytokine Activation in Hemodialysis Patients, Mary A. Fletcher, R. Patarca, P. Guido, and Nancy G. Klimas
Differential Patterns of Soluble Immune Mediators in HIV‑Infected Individuals with EBV‑Positive or Negative B cell Lymphomas, Mary A. Fletcher, R. Patarca, W. Harrington, and V. DeLaCruz
Self‑Efficacy and Disease Progression in AIDS, Mary A. Fletcher, K. Starr, A. LaPerriere, Gail Ironson, M. Antoni, and N. Schneiderman
HIV 1 Disease Progression and Psychosocial Variables, Gail Ironson, J. Simoneau, Nancy G. Klimas, M. Antoni, A. LaPerriere, Neil Schneiderman, and Mary A. Fletcher
Submissions from 1990
Age and HIV‑1 Effects on Lymphocyte Phenotypes in Congenital Clotting Disorders (CCD) Patients, Mary A. Fletcher
Immunology of Chronic Fatigue Syndrome Seminario Sobre Psicoimmunologia, Mary A. Fletcher
Lymphocyte Phenotypes in HTLV Seropositive Blood Donors and Recipients, Mary A. Fletcher