The Institute for Neuro Immune Medicine at Nova Southeastern University strives to advance knowledge and care for people with complex neuro-inflammatory illnesses through the integration of research, clinical care and education.

Current research focus at the Institute for Neuro Immune Medicine (INIM) includes Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Gulf War Illness (GWI). Investigators, clinicians and educators are committed to applying scientific advances to promote efficiency, enhance patient care and improve clinical utility. This advancement is done through clinical, laboratory, computational and integrative cardiovascular immunological research, all of which are conducted at the INIM by renowned researchers in their respective fields.

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Submissions from 2015

 

Spiritual coping predicts CD4-cell preservation and undetectable viral load over four years, Mary A. Fletcher, H. Kremer, Gail Ironson, L. Kaplan, R. Stuetzele, and N. Baker

Submissions from 2014

 

Gender differences in Gulf War Illness: VA, Nancy G. Klimas

Submissions from 2013

 

Biomarkers in Gulf War Illness, Mary A. Fletcher

 

Compassionate Love as a Predictor of Reduced HIV Disease Progression and Transmission Risk, Mary A. Fletcher, H. Kremer, Gail Ironson, L. Kaplan, and R. Stuetzele

 

Stress Management, Depression and Immune Status in Lower Income Racial/Ethnic Minority Women Co-infected with HIV and HPV, Mary A. Fletcher, C. R. Lopez, M. H. Antoni, D. Pereira, J. Seay, N. Whitehead, J. Potter, and M. O'Sullivan

Submissions from 2012

 

Biomarkers in ME/CFS, Mary A. Fletcher

 

Biomarkers for chronic fatigue, Mary A. Fletcher, Nancy G. Klimas, and Gordon Broderick

 

Treating Chronic Fatigue Syndrome/ ME and Gulf War Illness, Nancy G. Klimas

Submissions from 2011

 

Immunology of CFS/ME, Mary A. Fletcher

 

View of God as benevolent and forgiving or punishing and judgmental predicts HIV disease progression, Mary A. Fletcher, Gail Ironson, R. Stuetzle, D. Ironson, E. Balbin, H. Kremer, A. George, and N. Schneiderman

 

Biomarkers in CFS/ME, Mary A. Fletcher and Nancy G. Klimas

 

A pilot study of cognitive behavioral stress management effects on stress, quality of life, and symptoms in persons with chronic fatigue syndrome, Mary A. Fletcher, C. Lopez, M. Antoni, F. Penedo, D. Weiss, S. Cruess, M. C. Segotas, L. Helder, S. Siegel, and Nancy G. Klimas

 

Death and Dying, Nancy G. Klimas

 

Difficult Case Presentations Chair and panelist, Nancy G. Klimas

 

Endocrine issues in CFS/ME and GWI, Nancy G. Klimas

 

Immune mechanisms of autoimmune diseases: pathogens, self, and chronic disease, Nancy G. Klimas

 

What’s new? Pathogenesis and Treatment 2011, Nancy G. Klimas

Submissions from 2010

 

A formal analysis of cytokine networks in chronic fatigue syndrome, Mary A. Fletcher, G. Broderick, J. Fuite, A. Kreitz, S. D. Vernon, and Nancy G. Klimas

 

Cytokine Expression as a Potential Prognostic Indicator in Post-infectious Fatigue, Mary A. Fletcher, B. Katz, F. A. Smith, R. Taylor, S. D. Vernon, and G. Broderick

 

Biomarkers for Chronic Fatigue Syndrome and Gulf War Illness, Mary A. Fletcher, Nancy G. Klimas, and Gordon Broderick

 

Immunologic biomarkers for CFS/ME, Mary A. Fletcher, Nancy G. Klimas, and Gordon Broderick

 

Cytokine Expression as a Potential Prognostic Indicator in Post-infectious Fatigue, B. Katz, Mary A. Fletcher, F. A. Smith, R. Taylor, S. D. Vernon, and Gordon Broderick

 

Advances in our Understanding of Chronic Fatigue Syndrome, Nancy G. Klimas

 

Gene Expression change in exercise challenge in CFS/ME and GWI, Nancy G. Klimas

 

Immunology and Biomarker Discovery in ME/CFS, Nancy G. Klimas

 

INVEST in ME, Nancy G. Klimas

Submissions from 2009

 

Isolating Characteristic Immune Signals under Challenge in Gulf War Illness, Gordon Broderick, Mary A. Fletcher, S. D. Vernon, and Nancy G. Klimas

 

Neuropeptide Y (NPY) correlates with symptom severity in chronic fatigue syndrome, Mary A. Fletcher, Gail Ironson, M. Antoni, Nancy G. Klimas, and Y. Neuropeptide

 

Neuroimmune biomarkers in CFS. From infection to Neurometabolism: a nexus for CFS, Mary A. Fletcher, Nancy G. Klimas, and Gordon Broderick

 

Oxytocin is Associated with Better Immune Function in Low Income HIV+ Women with High Perceived Social Support, Mary A. Fletcher, C. Lopez, E. Fekete, M. Antoni, A. Mendez, A. Sussex, and N. Schneiderman

 

Incidence of sleep disorders in CFS sample, L. Garcia and Nancy G. Klimas

 

Treatment based on pathogenesis – advances in our understanding of CFS, Nancy G. Klimas

Submissions from 2008

 

Dipeptidyl peptidase IV(DDPIV/CD26) and neuropeptide y (NPY): Biomarkers for chronic fatigue syndrome, Mary A. Fletcher

 

Progress in identification of biomarkers for CFS and GWI, Mary A. Fletcher

 

Neuropeptide Y and dipeptidyl peptidase IV (CD26) in chronic fatigue syndrome, Mary A. Fletcher and Y. Neuropeptide

 

Support From Health Care Providers, Medication Attributions, HAART Adherence And Viral Load In HIV+ Low-Income Minority Women, Mary A. Fletcher, A. Sussex, E. E. Fekete, M. Antoni, J. Gonzales, F. Penedo, Nancy G. Klimas, S. MacPherson, R. Horne, and N. Schneiderman

 

Biomarker Discovery in CFS, Nancy G. Klimas

 

Immunology of Fatiguing Disorders, Nancy G. Klimas

 

Research Advances in CFS and ME, Nancy G. Klimas

 

Research Advances in CFS/ME, Nancy G. Klimas

Submissions from 2007

 

Perceived stress and norepinepherine predict the effectiveness of the response to protenase inhibitor medication in HIV, Mary A. Fletcher, Gail Ironson, E. Balbin, E. Stieren, K. Detz, N. Scheniderman, and M. Kumar

 

Cortisol mediates the relationship between stress management skills and prostate-specific antigen (PSA) level among men treated for prostate cancer, Mary A. Fletcher, L. Traeger, F. Penedo, M. Rasheed, E. Zhou, N. Scheniderman, and M. Antoni

 

Immunological Comparison of GWI and CFS, Mary A. Fletcher, X-R Zeng, M. Rosenthal, X. Q. Jin, G. Godoy, and Nancy G. Klimas

 

Advances in our understanding of the immunology of CFS, Nancy G. Klimas

 

Diagnosis and Management of CFS, Nancy G. Klimas

 

Evidence Based Treatment Approaches in CFS/ME, Nancy G. Klimas

 

Keynote address: Understanding the interactions of the Immune system and the brain in CFS, Nancy G. Klimas

 

New Directions in CFS/ME Research, Nancy G. Klimas

 

Isoprinosine in CFS (presentation), M. Vera and Nancy G. Klimas

Submissions from 2006

 

View of God is Associated with Disease Progression in HIV, Mary A. Fletcher, Gail Ironson, and R. Stuezle

 

Elevations of HHV-6 serology are associated with low NK cell Function. International Conference on HHV6 Infection, Mary A. Fletcher, Nancy G. Klimas, and K. Maher

 

Immune effects of an acute exercise challenge in Gulf War Illness, Mary A. Fletcher, Nancy G. Klimas, and M. Rosenthal

 

2006 GWI Research Advisory Council, Nancy G. Klimas

 

CFS In the Veteran Population: Best Practices in the Continuum of Care, Nancy G. Klimas

 

Chronic Fatigue Syndrome: From Genomics to Treatmen, Nancy G. Klimas

 

The Immunology and Genomics of Gulf War Illness, Nancy G. Klimas

Submissions from 2005

 

Clinical Management of CFS, Nancy G. Klimas

 

Gene Array Technology in CFS, Nancy G. Klimas

 

Impact of Research Advances on Clinical Management of CFS, Nancy G. Klimas

 

Research Advances in CFS, Nancy G. Klimas

 

Neuropeptide Y in CFS and GWI, Nancy G. Klimas and Mary A. Fletcher

Submissions from 2004

 

Gay disclosure to family, friends and coworkers: relation to changes in both CD 4 and viral load in HIV/AIDS, Mary A. Fletcher, E. Balbin, G. Ironson, and K. Ditz

 

Massage therapy intervention to enhance well-being in HIV+ Dominican children: preliminary results, Mary A. Fletcher, G. Shor-Posner, M. Hernandez-Reif, J. Baez, S. Soto, M. J. Miguez, E. Perez, R. Diaz, and G. Zhang

 

A Group-Based Cognitive Behavioral Stress Management Intervention Improves Psychosocial and Medical Outcomes in Chronic Fatigue Syndrome, Mary A. Fletcher, S. Siegel, M. C. Segesta, M. Antoni, K. Maher, D. Weiss, and Nancy G. Klimas

 

Psychological Distress and HIV Disease Progression: Roe of Natural Killer Cell Immunity, Jeffrey Greeson, Maria Llabre, Nancy G. Klimas, Peter Lawrence, Alex Gonzalez, Pedro Martin, Neil Schneiderman, and Barry Hurwitz

 

CFS – advancing knowledge impact on manageme, Nancy G. Klimas

 

CFS Pathogenesis, Nancy G. Klimas

 

Immunomodulatory therapies – a review, Nancy G. Klimas

 

Management of CFS, Nancy G. Klimas

 

Research Advances in CFS, Nancy G. Klimas

Submissions from 2003

 

Immunology of CFS, Mary A. Fletcher, K. Maher, and Nancy G. Klimas

 

CFS and Fibromyalgia, Nancy G. Klimas

 

CFS: What we know, what we need to know, and how to get there, Nancy G. Klimas

 

CFS: What we know, what we need to know, and how to get there, Nancy G. Klimas

 

Immune Methodologic Issues, Nancy G. Klimas

 

The Diagnosis and Management of CFS, Nancy G. Klimas

 

Assessment Tools in CFS, Nancy G. Klimas and E. Turgeli

Submissions from 2002

 

Psychosocial factors related to sustained health in HIV. . 7th International Congress of Behavioral Medicine, Mary A. Fletcher, Gail Ironson, G. Solomon, E. Balbin, C. O'Cleirigh, and N. Schneiderman

 

A group-based intervention enhances coping and energy level and decreases depression in chronic fatigue syndrome, Mary A. Fletcher, D. Weiss, D. Pereira, M. Antoni, S. Siegel, and Nancy G. Klimas

 

Adherence to Therapy Seminar, Nancy G. Klimas

 

CFS – Somatic or Physical? A Debate, Nancy G. Klimas

 

debater participant: CFS – physical or somatic disorder?, Nancy G. Klimas

 

Diagnosis and Management of CFS, Nancy G. Klimas

 

Instruments and Design of an Empiric Case Definition Study, Nancy G. Klimas

 

speaker : Methodologic Issues – Immunology of CFS, Nancy G. Klimas

Submissions from 2001

 

Current Understanding of CFS Pathogenesis, NIH/CFS Research Priorities Series, Nancy G. Klimas

 

Current Understanding of CFS Pathogenesis, NIH/CFS Research Priorities Series, Nancy G. Klimas

 

Global Impact of HIV on Women, Nancy G. Klimas

 

Inclusion and Exclusion Criteria, Nancy G. Klimas

 

Methodologic Issues in the Study of CFS, Nancy G. Klimas

 

Methodologic Issues Seminar, Nancy G. Klimas

Submissions from 2000

 

Social support mediates the relationship between loneliness and human herpesvirus-6 (HHV-6) antibody titers, Mary A. Fletcher, D. Dixon, S. Crues, Nancy G. Klimas, Gail Ironson, A. Baum, N. Schneiderman, and M. Antoni

 

Can non-specific cellular immunity protect HIV-infected persons with very low CD4 counts?, Mary A. Fletcher, Gail Ironson, G. Solomon, E. Balbin, Nancy G. Klimas, and N. Schneiderman

 

Symposium: Multidisciplinary studies of chronic fatigue syndrome, Mary A. Fletcher, R. Patarca, K. Maher, M. Antoni, and Nancy G. Klimas

 

Adherence and Chronic Active Hepatitis C – what we have learned from HIV, Nancy G. Klimas

 

Current Understanding of CFS Pathogenesis, NIH/CFS Research Priorities Series, Nancy G. Klimas

 

Immunology of CFS, Nancy G. Klimas

 

Immunology of CFS, Nancy G. Klimas

 

Immunology of Chronic Fatigue Syndrome, Nancy G. Klimas

Submissions from 1999

 

Acute and sustained effects of anxiety on immune status and social support in HIV+ gay men following Hurricane Andrew, Mary A. Fletcher, D. Dixon, M. Antoni, S. Wagner, K. Kilbourn, N. Schneiderman, and Nancy G. Klimas