Evaluation of Practice Effect on Neuropsychological Measures among Persons With and Without HIV Infection in Northern India

Author(s)

Raymond L. Ownby, Nova Southeastern UniversityFollow
Drenna Waldrop-Valverde, Emory University
Deborah L. Jones
Sunil Sharma
Ritu Nehra
Adarsh M. Kumar
Sudesh Prabhakar
Amarilis Acevedo, Nova Southeastern UniversityFollow
Mahendra Kumar

Document Type

Article

Publication Title

Journal of NeuroVirology

ISSN

1538-2443

Publication Date

2-2017

Abstract

An evaluation of the effects of HIV infection on neurocognition over time is important for understanding disease progression. Changes in cognitive function can be evaluated longitudinally by using neuropsychological testing at repeated intervals. The assessment of change over time, however, is complicated by the potentially confounding influence of learning on repeated test administrations, often referred to as practice effect. In this study, we present data on testing of persons with or without HIV infection on a battery administered at study baseline and repeated 1 year later. Results suggest that practice effects may be diminished in persons with HIV infection compared to without it. This appears to be true even among those with relatively intact immune functioning as measured by CD4 count.

DOI

https://doi.org/10.1007/s13365-016-0487-7

Volume

23

Issue

1

First Page

134

Last Page

140

NSUWorks Citation

Ownby, R. L., Waldrop-Valverde, D., Jones, D. L., Sharma, S., Nehra, R., Kumar, A. M., Prabhakar, S., Acevedo, A., Kumar, M. (2017). Evaluation of Practice Effect on Neuropsychological Measures among Persons With and Without HIV Infection in Northern India. Journal of NeuroVirology, 23(1), 134-140.
Available at: https://nsuworks.nova.edu/cps_facarticles/1544