Genome 10K: A proposal to obtain whole-genome sequence for 10000 vertebrate species

Authors

• David Haussler, University of California, Santa Cruz
• Stephen J. O'Brien, National Cancer Institute at FrederickFollow
• Oliver A. Ryder, San Diego Zoo Institute for Conservation Research
• F. Keith Barker, University of Minnesota Twin Cities
• Michele Clamp, Broad Institute
• Andrew J. Crawford, Universidad de Los Andes, Colombia
• Robert Hanner, Biodiversity Institute of Ontario
• Olivier Hanotte, University of Nottingham
• Warren E. Johnson, National Cancer Institute at Frederick
• Jimmy A. McGuire, University of California, Berkeley
• Webb Miller, Pennsylvania State University
• Robert W. Murphy, Royal Ontario Museum
• William J. Murphy, Texas A&M College of Veterinary Medicine & Biomedical Sciences
• Frederick H. Sheldon, Louisiana State University
• Barry Sinervo, University of California, Santa Cruz
• Byrappa Venkatesh, A-Star, Institute of Molecular and Cell Biology
• Edward O. Wiley, University KS Natural History Museum
• Fred W. Allendorf, University of Montana
• George Amato, American Museum of Natural History
• C. Scott Baker, Oregon State University
• Aaron Bauer, Villanova University
• Albano Beja-Pereira, Universidade do Porto, Centro de Investigação em Biodiversidade e Recursos Genéticos
• Eldredge Bermingham, Smithsonian Tropical Research Institute
• Giacomo Bernardi, University of California, Santa Cruz
• Cibele R. Bonvicino, Instituto Nacional de Cancer
• Sydney Brenner, Salk Institute for Biological Studies
• Terry Burke, The University of Sheffield
• Joel Cracraft, American Museum of Natural History
• Mark Diekhans, University of California, Santa Cruz

Document Type

Article

Publication Title

Journal of Heredity

ISSN

14657333

Publication Date

11-1-2009

Keywords

Ancestral state reconstruction, Comparative genomics, G10K, Molecular evolution, Species conservation, Vertebrate biology

Abstract

The human genome project has been recently complemented by whole-genome assessment sequence of 32 mammals and 24 nonmammalian vertebrate species suitable for comparative genomic analyses. Here we anticipate a precipitous drop in costs and increase in sequencing efficiency, with concomitant development of improved annotation technology and, therefore, propose to create a collection of tissue and DNA specimens for 10000 vertebrate species specifically designated for whole-genome sequencing in the very near future. For this purpose, we, the Genome 10K Community of Scientists (G10KCOS), will assemble and allocate a biospecimen collection of some 16203 representative vertebrate species spanning evolutionary diversity across living mammals, birds, nonavian reptiles, amphibians, and fishes (ca. 60000 living species). In this proposal, we present precise counts for these 16203 individual species with specimens presently tagged and stipulated for DNA sequencing by the G10KCOS. DNA sequencing has ushered in a new era of investigation in the biological sciences, allowing us to embark for the first time on a truly comprehensive study of vertebrate evolution, the results of which will touch nearly every aspect of vertebrate biological enquiry. © The American Genetic Association. 2009. All rights reserved.

DOI

10.1093/jhered/esp086

Volume

100

Issue

6

First Page

659

Last Page

674

NSUWorks Citation

Haussler, David; Stephen J. O'Brien; Oliver A. Ryder; F. Keith Barker; Michele Clamp; Andrew J. Crawford; Robert Hanner; Olivier Hanotte; Warren E. Johnson; Jimmy A. McGuire; Webb Miller; Robert W. Murphy; William J. Murphy; Frederick H. Sheldon; Barry Sinervo; Byrappa Venkatesh; Edward O. Wiley; Fred W. Allendorf; George Amato; C. Scott Baker; Aaron Bauer; Albano Beja-Pereira; Eldredge Bermingham; Giacomo Bernardi; Cibele R. Bonvicino; Sydney Brenner; Terry Burke; Joel Cracraft; and Mark Diekhans. 2009. "Genome 10K: A proposal to obtain whole-genome sequence for 10000 vertebrate species." Journal of Heredity 100, (6): 659-674. doi:10.1093/jhered/esp086.