Metanalysis of Genome Editing Using Crispr/Cas9 Technology Towards HIV-1 Treatment
Abstract
Genome editing, also called gene editing is a new branch of research that aims to explore means to modify genes of living organisms. Genome editing appears to have a promising future for researchers as it will further help to understand the gene function and develop ways to treat genetic or acquired diseases. Moreover, gene editing such as CRISPR/Cas9 technology can aid in manipulating the genome sequence, thereby, advancing treatments that will improve patients’ life span and quality of life. CRISPR/Cas9 technology supports three main mechanisms for genome editing, including plasmids-based methods, the direct intracellular distribution of the Cas9 mRNA, and the direct delivery of the Cas9 protein. By conducting a metanalysis, on published studies utilizing the principles of CRISPR/Cas9 technology, this poster will highlight how gene/genome editing can provide advances and advantages towards the understanding of Human Immunodeficiency Virus (HIV). Specifically, this genome editing metanalysis will focus on research studies related to the CCR5 receptor that can be genetically altered and can provide great contributions towards possible disease management solutions or “cures”. However, knowing the benefits and disadvantages is vital to balance the factors of gene-editing technology. Additionally, this poster will conclude with an overview of how research can benefit from the emergence of CRISPR/Cas9 technology as augmentation of various beneficial applications in the fields of science, medicine, agriculture, pharmaceuticals, etc.
Faculty Sponsors
Dr. Samiksha Prasah, Dr. Michelle Ramim
Project Type
Event
Location
Alvin Sherman Library
Start Date
4-6-2022 12:00 PM
End Date
4-7-2022 5:00 PM
Metanalysis of Genome Editing Using Crispr/Cas9 Technology Towards HIV-1 Treatment
Alvin Sherman Library
Genome editing, also called gene editing is a new branch of research that aims to explore means to modify genes of living organisms. Genome editing appears to have a promising future for researchers as it will further help to understand the gene function and develop ways to treat genetic or acquired diseases. Moreover, gene editing such as CRISPR/Cas9 technology can aid in manipulating the genome sequence, thereby, advancing treatments that will improve patients’ life span and quality of life. CRISPR/Cas9 technology supports three main mechanisms for genome editing, including plasmids-based methods, the direct intracellular distribution of the Cas9 mRNA, and the direct delivery of the Cas9 protein. By conducting a metanalysis, on published studies utilizing the principles of CRISPR/Cas9 technology, this poster will highlight how gene/genome editing can provide advances and advantages towards the understanding of Human Immunodeficiency Virus (HIV). Specifically, this genome editing metanalysis will focus on research studies related to the CCR5 receptor that can be genetically altered and can provide great contributions towards possible disease management solutions or “cures”. However, knowing the benefits and disadvantages is vital to balance the factors of gene-editing technology. Additionally, this poster will conclude with an overview of how research can benefit from the emergence of CRISPR/Cas9 technology as augmentation of various beneficial applications in the fields of science, medicine, agriculture, pharmaceuticals, etc.
