Adhesion of Lysozyme to FDA Group III Contact Lenses and Vials

Adhesion of Lysozyme to FDA Group III Contact Lenses and Vials

Alvin Sherman Library 1054

Lysozyme is the major protein adhering to contact lenses. Lysozyme adhesion to contact lenses and glass vials was examined with bicinchoninic acid (BCA). Contact lenses were placed in vials on day 0, and some lenses were removed every day thereafter for five days. The concentration of lysozyme in the vials, and its adhesion to the lenses, was monitored daily. Lysozyme adhesion to FDA Group III lenses showed an up-down pattern, with high levels of adhesion after 1 day of incubation, and lower, but stable, levels of adhesion after 2, 3, and 4 days of incubation. Lens adhesion was significantly lower after 1 day of incubation (P < 0.05), but not different thereafter (P > 0.05). The concentration of lysozyme in the vials was not different after four days of incubation, compared to the start of the experiment (P > 0.05).