Faculty Books and Book Chapters
Understanding and Managing Antineoplastic and Antiretroviral Therapy
Edition
1
ISBN or ISSN
9780190493097
Location
New York, NY
Chapter
29
Publication Date / Copyright Date
2017
First Page
309
Last Page
317
Publisher
Oxford University Press
DOI Number
10.1093/med/9780190493097.003.0029
Abstract
The use of combination antiretroviral therapy in patients with malignancies is associated with improved HIV and cancer-related outcomes. Combining antiretroviral and antineoplastic therapy is often complicated by significant drug-drug interactions, drug-disease state monitoring interactions and overlapping toxicities. Definitive pharmacokinetic studies evaluating drug interactions between antineoplastics and antiretrovirals are uncommon and clinical judgment must often be used to determine the potential for significant interactions. Adjusting antiretroviral therapy in response to significant drug interactions or overlapping toxicities is often more feasible than modifying antineoplastic protocols.
Disciplines
Medicine and Health Sciences | Pharmacy and Pharmaceutical Sciences
Keywords
antineoplastic therapy, antiretroviral therapy, pharmacology
Files
NSUWorks Citation
Schafer, Jason J.; Sherman, Elizabeth M.; Gill, Taylor K.; and Birney, Jatandra, "Understanding and Managing Antineoplastic and Antiretroviral Therapy" (2017). Faculty Books and Book Chapters. 27.
https://nsuworks.nova.edu/hpd_corx_facbooks/27