Faculty Articles
Experimental sleep fragmentation and sleep deprivation in rats increases exploration in an open field test of anxiety while increasing plasma corticosterone levels
Document Type
Article
Publication Title
Behav Brain Res
ISSN
0166-4328
Publication Date
1-1-2009
Abstract
Sleep deprivation alters mood and anxiety in man. In rats, 24 h of treadmill-induced total sleep deprivation or sleep fragmentation increased exploratory behavior in an open field test of anxiety compared to cage or exercise controls. Plasma corticosterone (CORT) levels of sleep disturbed and exercise control rats were elevated compared to cage controls, suggesting that the increased exploration observed in the sleep disturbed rats was not due to a hypothalamic-pituitary-adrenal (HPA) stress response.
DOI
10.1016/j.bbr.2008.08.035
Volume
197
Issue
2
First Page
450
Last Page
453
NSUWorks Citation
Tartar, J. L.,
Ward, C.,
Cordeira, J.,
Legare, S.,
Blanchette, A.,
McCarley, R.,
Strecker, R.
(2009). Experimental sleep fragmentation and sleep deprivation in rats increases exploration in an open
field test of anxiety while increasing plasma corticosterone levels. Behav Brain Res, 197(2), 450-453.
Available at: https://nsuworks.nova.edu/cps_facarticles/1203