Chemistry and Physics Faculty Articles
Title
Prevalence of Diarylprolinol Silyl Ethers as Catalysts in Total Synthesis and Patents
Document Type
Article
Publication Date
2-12-2019
Publication Title
Chemical Reviews
ISSN
0009-2665
Volume
119
Issue/No.
6
First Page
4221
Last Page
4260
Abstract
Diarylprolinol silyl ethers are among the most utilized stereoselective organocatalysts for the construction of complex molecules. With their debut in 2005, these catalysts have been applied in numerous method developments primarily leveraging enamine and iminium-ion catalysis. These strategies have extended into the preparation of complex molecules in both academic and industrial settings. This Review intends to give an overview of the application of the diarylprolinol silyl ether catalysts in total synthesis. Furthermore, integration of these catalysts in patent literature is also disclosed highlighting the versatility of the catalytic system.
NSUWorks Citation
Reyes-Rodriguez, G. J., Rezayee, N. M., Vidal-Albalat, A., & Jørgensen, K. A. (2019). Prevalence of Diarylprolinol Silyl Ethers as Catalysts in Total Synthesis and Patents. Chemical Reviews, 119, (6), 4221 - 4260. https://doi.org/10.1021/acs.chemrev.8b00583. Retrieved from https://nsuworks.nova.edu/cnso_chemphys_facarticles/263
ORCID ID
0000-0002-0566-0820
ResearcherID
V-6501-2018
DOI
10.1021/acs.chemrev.8b00583
Comments
©2019 American Chemical Society