Biology Faculty Articles

Document Type

Article

Publication Date

1-2018

Publication Title

Annals of International Medical and Dental Research

Keywords

Selective serotonin reuptake inhibitors, SSRI, antidepressant, treatment of depression, selective serotonin norepinephrine reuptake inhibitors, SNRI, tricyclic antidepressants, TCA

ISSN

2395-2814

Volume

4

Issue/No.

2

First Page

4

Last Page

6

Abstract

Depression is one of the most important causes of disability-adjusted life years. Currently, the majority of patients are treated with SSRIs. However, the effectiveness of SSRIs is questionable. Method: The purpose of this study was to determine the effectiveness of the pharmacotherapy treatment selective serotonin reuptake inhibitors (SSRIs) in patients diagnosed with major depression. This was achieved by comparison to other methods of antidepressant treatment such as, selective serotonin norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), electroconvulsive therapy (ECT), and psychotherapy. Results: The majority of patients were taking SSRIs for treatment of depression alone or in combination with other antidepressant medications. More than half those patients showed pharmacological effectiveness. However, patients who were taking other types of antidepressants also experienced reduction in their symptoms. Conclusion: The analysis of data that was collected from an outpatient mental health private practice, showed no advantage in effectiveness of SSRIs compared with other treatment options.

Comments

Copyright: © the author(s), publisher. Annals of International Medical and Dental Research (AIMDR) is an Official Publication of “Society for Health Care & Research Development”. It is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

DOI

10.21276/aimdr.2018.4.2.SG2

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