Whole-genome analysis of mycobacterium tuberculosis from patients with tuberculous spondylitis, Russia

Authors

• Ekaterina Chernyaeva, Saint-Petersburg State Research Institute of Phthisiopulmonology
• Mikhail Rotkevich, Saint Petersburg State University
• Ksenia Krasheninnikova, Saint Petersburg State University
• Andrey Yurchenko, Saint Petersburg State University
• Anna Vyazovaya, Saint-Petersburg Pasteur Institute
• Igor Mokrousov, Saint-Petersburg Pasteur Institute
• Natalia Solovieva, Saint-Petersburg State Research Institute of Phthisiopulmonology
• Viacheslav Zhuravlev, Saint-Petersburg State Research Institute of Phthisiopulmonology
• Piotr Yablonsky, Saint Petersburg State University
• Stephen J. O’Brien, Saint Petersburg State UniversityFollow

Document Type

Article

Publication Title

Emerging Infectious Diseases

ISSN

10806059

Publication Date

3-1-2018

Abstract

Whole-genome analysis of Mycobacterium tuberculosis isolates collected in Russia (N = 71) from patients with tuberculous spondylitis supports a detailed characterization of pathogen strain distributions and drug resistance phenotype, plus distinguished occurrence and association of known resistance mutations. We identify known and novel genome determinants related to bacterial virulence, patho-genicity, and drug resistance.

DOI

10.3201/eid2403.170151

Volume

24

Issue

3

First Page

579

Last Page

583

NSUWorks Citation

Chernyaeva, Ekaterina; Mikhail Rotkevich; Ksenia Krasheninnikova; Andrey Yurchenko; Anna Vyazovaya; Igor Mokrousov; Natalia Solovieva; Viacheslav Zhuravlev; Piotr Yablonsky; and Stephen J. O’Brien. 2018. "Whole-genome analysis of mycobacterium tuberculosis from patients with tuberculous spondylitis, Russia." Emerging Infectious Diseases 24, (3): 579-583. doi:10.3201/eid2403.170151.