Assignment of the Feline α-L-Iduronidase Gene to Chromosome D4

Authors

• Edward H. Shuchman, Mount Sinai School of Medicine
• Stephen J. O'Brien, National Cancer Institute at FrederickFollow
• Robert J. Desnick, Mount Sinai School of Medicine

ORCID

0000-0001-7353-8301

ResearcherID

N-1726-2015

Document Type

Article

Publication Title

Genomics

ISSN

0888-7543

Publication Date

4-1989

Abstract

The structural gene encoding feline α-l-iduronidase has been assigned to chromosome D4 by electrophoretic analysis of feline-hamster somatic cell hybrids. Previously, the human α-L-iduronidase gene had been assigned to the chromosomal region 22pter-q11. α-L-Iduronidase is the first human gene on chromosome 22 to be comparatively mapped in cats and the localization of the feline gene should facilitate further genetic analysis of the feline MPSI animal model.

Volume

4

Issue

3

First Page

442

Last Page

444

Comments

© 1989 Published by Elsevier Inc.

NSUWorks Citation

Shuchman, Edward H.; Stephen J. O'Brien; and Robert J. Desnick. 1989. "Assignment of the Feline α-L-Iduronidase Gene to Chromosome D4." Genomics 4, (3): 442-444. https://nsuworks.nova.edu/cnso_bio_facarticles/376