Title

Whole-genome analysis of mycobacterium tuberculosis from patients with tuberculous spondylitis, Russia

Authors

Ekaterina Chernyaeva, Saint-Petersburg State Research Institute of Phthisiopulmonology
Mikhail Rotkevich, Saint Petersburg State University
Ksenia Krasheninnikova, Saint Petersburg State University
Andrey Yurchenko, Saint Petersburg State University
Anna Vyazovaya, Saint-Petersburg Pasteur Institute
Igor Mokrousov, Saint-Petersburg Pasteur Institute
Natalia Solovieva, Saint-Petersburg State Research Institute of Phthisiopulmonology
Viacheslav Zhuravlev, Saint-Petersburg State Research Institute of Phthisiopulmonology
Piotr Yablonsky, Saint Petersburg State University
Stephen J. O’Brien, Saint Petersburg State UniversityFollow

Document Type

Article

Publication Date

3-1-2018

Publication Title

Emerging Infectious Diseases

ISSN

10806059

Volume

24

Issue/No.

3

First Page

579

Last Page

583

Abstract

Whole-genome analysis of Mycobacterium tuberculosis isolates collected in Russia (N = 71) from patients with tuberculous spondylitis supports a detailed characterization of pathogen strain distributions and drug resistance phenotype, plus distinguished occurrence and association of known resistance mutations. We identify known and novel genome determinants related to bacterial virulence, patho-genicity, and drug resistance.

NSUWorks Citation

Chernyaeva, Ekaterina; Mikhail Rotkevich; Ksenia Krasheninnikova; Andrey Yurchenko; Anna Vyazovaya; Igor Mokrousov; Natalia Solovieva; Viacheslav Zhuravlev; Piotr Yablonsky; and Stephen J. O’Brien. 2018. "Whole-genome analysis of mycobacterium tuberculosis from patients with tuberculous spondylitis, Russia." Emerging Infectious Diseases 24, (3): 579-583. doi:10.3201/eid2403.170151.

DOI

10.3201/eid2403.170151