Quantitative Analysis of the Spatiotemporal Dynamics of a Synthetic Predator-Prey Ecosystem, In: Synthetic Gene Networks
Methods in Molecular Biology
Synthetic ecosystem Quorum sensing Predator–prey ecosystem Microbial consortia Biodiversity Synthetic biology Bidirectional communication Gene circuit
A major focus in synthetic biology is the rational design and implementation of gene circuits to control dynamics of individual cells and, increasingly, cellular populations. Population-level control is highlighted in recent studies which attempt to design and implement synthetic ecosystems (or engineered microbial consortia). On the one hand, these engineered systems may serve as a critical technological foundation for practical applications. On the other hand, they may serve as well-defined model systems to examine biological questions of broad relevance. Here, using a synthetic predator–prey ecosystem as an example, we illustrate the basic experimental techniques involved in system implementation and characterization. By extension, these techniques are applicable to the analysis of other microbial-based synthetic or natural ecosystems.
Payne, S.; Robert P. Smith; and L. You. 2012. "Quantitative Analysis of the Spatiotemporal Dynamics of a Synthetic Predator-Prey Ecosystem, In: Synthetic Gene Networks." Methods in Molecular Biology 813, (): 315-330. http://nsuworks.nova.edu/cnso_bio_facarticles/37