Fish Lateral Line Innovation: Insights into the Evolutionary Genomic Dynamics of a Unique Mechanosensory Organ

Authors

• Siby Philip, Universidade do Porto - Portugal
• Joao P. Machado, Universidade do Porto - Portugal
• Emanuel Maldonado, Universidade do Porto - Portugal
• Vitor Vasconcelos, Universidade do Porto - Portugal
• Stephen J. O'Brien, National Cancer Institute at Frederick; St. Petersburg State University - RussiaFollow
• Warren E. Johnson, National Cancer Institute at Frederick
• Agostinho Antunes, National Cancer Institute at Frederick; Universidade do Porto - Portugal

ORCID

0000-0001-7353-8301

ResearcherID

N-1726-2015

Document Type

Article

Publication Title

Molecular Biology and Evolution

ISSN

0737-4038

Publication Date

12-2012

Keywords

Lateral line, Teleost, Adaptive evolution, Positive selection

Abstract

The mechanosensory lateral line, found only in fishes and amphibians, is an important sense organ associated with aquatic life. Lateral line patterns differ among teleost, the most diverse vertebrate taxa, hypothetically in response to selective pressures from different aquatic habitats. In this article, we conduct evolutionary genomic analyses of 34 genes associated with lateral line system development in teleosts to elucidate the significance of contrasting evolutionary rates and changes in the protein coding sequences. We find that duplicated copies of these genes are preferentially retained in the teleost genomes and that episodic events of positive selection have occurred in 22 of the 30 postduplication branches. In general, teleost genes evolved at a faster rate relative to their tetrapod counterparts, and the mutation rates of 26 of the 34 genes differed among teleosts and tetrapods. We conclude that following whole genome duplication, evolutionary rates and episodic events of positive selection on the lateral line system development genes might have been one of the factors favoring the subsequent adaptive radiation of teleosts into diverse habitats. These results provide the foundation for further detailed explorations into lateral line system genes and the evolution of diverse phenotypes and adaptations.

Volume

29

Issue

12

First Page

3887

Last Page

3898

Comments

©The Author 2012. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved.

Additional Comments

Portuguese Foundation for Science and Technology grant and project #s: (SFRH/BD/47938/2008) and J.P.M. (SFRH/BD/65245/2009), PTDC/AAC-AMB/104983/2008 (FCOMP-01-0124-FEDER-008610), PTDC/AAC-AMB/121301/2010 (FCOMP-01-0124-FEDER-019490)

NSUWorks Citation

Philip, Siby; Joao P. Machado; Emanuel Maldonado; Vitor Vasconcelos; Stephen J. O'Brien; Warren E. Johnson; and Agostinho Antunes. 2012. "Fish Lateral Line Innovation: Insights into the Evolutionary Genomic Dynamics of a Unique Mechanosensory Organ." Molecular Biology and Evolution 29, (12): 3887-3898. https://nsuworks.nova.edu/cnso_bio_facarticles/428