Title

Fish Lateral Line Innovation: Insights into the Evolutionary Genomic Dynamics of a Unique Mechanosensory Organ

Authors

Siby Philip, Universidade do Porto - Portugal
Joao P. Machado, Universidade do Porto - Portugal
Emanuel Maldonado, Universidade do Porto - Portugal
Vitor Vasconcelos, Universidade do Porto - Portugal
Stephen J. O'Brien, National Cancer Institute at Frederick; St. Petersburg State University - RussiaFollow
Warren E. Johnson, National Cancer Institute at Frederick
Agostinho Antunes, National Cancer Institute at Frederick; Universidade do Porto - Portugal

Document Type

Article

Publication Date

12-2012

Publication Title

Molecular Biology and Evolution

Keywords

Lateral line, Teleost, Adaptive evolution, Positive selection

ISSN

0737-4038

Volume

29

Issue/No.

12

First Page

3887

Last Page

3898

Abstract

The mechanosensory lateral line, found only in fishes and amphibians, is an important sense organ associated with aquatic life. Lateral line patterns differ among teleost, the most diverse vertebrate taxa, hypothetically in response to selective pressures from different aquatic habitats. In this article, we conduct evolutionary genomic analyses of 34 genes associated with lateral line system development in teleosts to elucidate the significance of contrasting evolutionary rates and changes in the protein coding sequences. We find that duplicated copies of these genes are preferentially retained in the teleost genomes and that episodic events of positive selection have occurred in 22 of the 30 postduplication branches. In general, teleost genes evolved at a faster rate relative to their tetrapod counterparts, and the mutation rates of 26 of the 34 genes differed among teleosts and tetrapods. We conclude that following whole genome duplication, evolutionary rates and episodic events of positive selection on the lateral line system development genes might have been one of the factors favoring the subsequent adaptive radiation of teleosts into diverse habitats. These results provide the foundation for further detailed explorations into lateral line system genes and the evolution of diverse phenotypes and adaptations.

Comments

©The Author 2012. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved.

Additional Comments

Portuguese Foundation for Science and Technology grant and project #s: (SFRH/BD/47938/2008) and J.P.M. (SFRH/BD/65245/2009), PTDC/AAC-AMB/104983/2008 (FCOMP-01-0124-FEDER-008610), PTDC/AAC-AMB/121301/2010 (FCOMP-01-0124-FEDER-019490)

NSUWorks Citation

Philip, Siby; Joao P. Machado; Emanuel Maldonado; Vitor Vasconcelos; Stephen J. O'Brien; Warren E. Johnson; and Agostinho Antunes. 2012. "Fish Lateral Line Innovation: Insights into the Evolutionary Genomic Dynamics of a Unique Mechanosensory Organ." Molecular Biology and Evolution 29, (12): 3887-3898. https://nsuworks.nova.edu/cnso_bio_facarticles/428

ORCID ID

0000-0001-7353-8301

ResearcherID

N-1726-2015