Biology Faculty Articles

Document Type

Article

Publication Date

2-2012

Publication Title

Viruses

Keywords

FIV, FCoV, FeLV, Felidae

ISSN

1999-4915

Volume

4

Issue/No.

2

First Page

236

Last Page

257

Abstract

The domestic cat is afflicted with multiple viruses that serve as powerful models for human disease including cancers, SARS and HIV/AIDS. Cat viruses that cause these diseases have been studied for decades revealing detailed insight concerning transmission, virulence, origins and pathogenesis. Here we review recent genetic advances that have questioned traditional wisdom regarding the origins of virulent Feline infectious peritonitis (FIP) diseases, the pathogenic potential of Feline Immunodeficiency Virus (FIV) in wild non-domestic Felidae species, and the restriction of Feline Leukemia Virus (FeLV) mediated immune impairment to domestic cats rather than other Felidae species. The most recent interpretations indicate important new evolutionary conclusions implicating these deadly infectious agents in domestic and non-domestic felids.

Comments

©2012 MDPI AG (Basel, Switzerland)

ORCID ID

0000-0001-7353-8301

ResearcherID

N-1726-2015

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