Abstract
Synthetic porphyrin molecules are commonly studied as photosensitizing agents in photodynamic therapy as a form of cancer treatment. The porphyrin molecules target cell organelles to induce cellular apoptosis, or navigate toward the cellular membrane, causing tissue necrosis. This porphyrin activity is primarily undetectable and only activated under the exposure of light. The chemical structure and properties of porphyrin compounds have varying effects on their success and viability in this treatment. The study of tetraphenylporphyrin derivatives and octalkyl porphyrin compounds can be implemented in finding suitable compounds for this technique.
Faculty Sponsors
Dr. Maria Ballester
Project Type
Event
Location
Alvin Sherman Library
Start Date
4-4-2014 1:00 PM
End Date
4-4-2014 5:30 PM
Tetraphenylporphyrin Derivatives and Octalkyl Porphyrin Interactions in Cancer Cells
Alvin Sherman Library
Synthetic porphyrin molecules are commonly studied as photosensitizing agents in photodynamic therapy as a form of cancer treatment. The porphyrin molecules target cell organelles to induce cellular apoptosis, or navigate toward the cellular membrane, causing tissue necrosis. This porphyrin activity is primarily undetectable and only activated under the exposure of light. The chemical structure and properties of porphyrin compounds have varying effects on their success and viability in this treatment. The study of tetraphenylporphyrin derivatives and octalkyl porphyrin compounds can be implemented in finding suitable compounds for this technique.
