Abstract
"It is not what you look at that matters, it is what you see." –Henry David Thoreau
Vision is key to the human experience. It is often the first sensation received for environmental navigation. While to the average eye images may be clear, ocular disorders can distort their production, making the study on ocular disorders essential. Glaucoma is characterized by damage to the optic nerve due to excessively high intraocular pressure (IOP). It is assumed that IOP is uniform throughout the eye. Therefore we can link glaucoma to the deformations of the cornea, which is the oculardisorder of astigmatism inhibiting the eye‘s ability to properly focus an image.Deformation is measured as a variation in central corneal curvature (CCC), a degree of spherical shape. To create an ocular model we build upon the Imbert-Fick law, which determines the force balance along the surface of a spherical body. The variables are now explicitly specified to describe surface tension and bending force as functions of the deformation of the CCC and pressure as a function of intraocular volume. This model depicts the effects of changes in IOP on CCC and then the inverse function where CCC in turn affects IOP. With this model we hope to determine a positive correlation between the two ocular disorders which will lead to a better understanding of their relationship in terms of early detection and prevention in clinical settings.
Faculty Sponsors
Dr. Evan Haskell
Project Type
Event
Location
Alvin Sherman Library
Start Date
4-3-2009 12:00 AM
End Date
4-3-2009 12:00 AM
Bending Under Pressure: "In-Vision" it’s Plain to See
Alvin Sherman Library
"It is not what you look at that matters, it is what you see." –Henry David Thoreau
Vision is key to the human experience. It is often the first sensation received for environmental navigation. While to the average eye images may be clear, ocular disorders can distort their production, making the study on ocular disorders essential. Glaucoma is characterized by damage to the optic nerve due to excessively high intraocular pressure (IOP). It is assumed that IOP is uniform throughout the eye. Therefore we can link glaucoma to the deformations of the cornea, which is the oculardisorder of astigmatism inhibiting the eye‘s ability to properly focus an image.Deformation is measured as a variation in central corneal curvature (CCC), a degree of spherical shape. To create an ocular model we build upon the Imbert-Fick law, which determines the force balance along the surface of a spherical body. The variables are now explicitly specified to describe surface tension and bending force as functions of the deformation of the CCC and pressure as a function of intraocular volume. This model depicts the effects of changes in IOP on CCC and then the inverse function where CCC in turn affects IOP. With this model we hope to determine a positive correlation between the two ocular disorders which will lead to a better understanding of their relationship in terms of early detection and prevention in clinical settings.
