NSUWorks - Health Professions Division REACH Day: Relative Efficacy of Two Marketed Hydrogen Peroxide Whitening Strips

 

Presentation Title

Relative Efficacy of Two Marketed Hydrogen Peroxide Whitening Strips

College

College of Dental Medicine

Location

Signature Grand, Davie, Florida, USA

Format

Poster

Start Date

25-4-2008 12:00 AM

End Date

25-4-2008 12:00 AM

Abstract

Objective. Efficacy of two marketed hydrogen peroxide whitening strip regimens was compared in this randomized, examiner-blinded clinical trial. Methods. A total of 57 healthy adult volunteers were randomized to one of the two treatments: Listerine Whitening® Quick Dissolving Strips (LWQD strip) or 6% hydrogen peroxide Crest® Whitestrips® (control strips). Both products were used twice daily for 14 days per manufacturer's instructions: LWQD were worn until completely dissolved and the control strips were worn for 30 min per application. Efficacy was measured objectively as L*a*b* color change using digital images of the maxillary anterior teeth at Baseline, Day 8, and Day 15. Results. The average age of study participants was 42.1 and 63% were females. At Day 8, adjusted mean (SE) Δb* was –0.82 (0.12) for the LWQD strip and –1.32 (0.12) for the control strip while adjusted mean (SE) ΔL* was 0.97 (0.14) and 1.75 (0.14) for the LWQD and the control strips, respectively. At the end-of-treatment at Day 15, adjusted mean (SE) Δb* was –1.50 (0.17) for the LWQD strip and –2.03 (0.16) for the control strip. For ΔL*, end-of-treatment, adjusted means (SE) were 1.33 (0.20) for the LWQD strip compared to 2.06 (0.18) for the control strip. Groups differed significantly for both Δb* and ΔL*at the end-of-treatment (p ≤ 0.03) and at Day 8 (p < 0.005) favoring the control strip. No product-related adverse events were reported. Conclusion. Use of the 6% hydrogen peroxide control strip provided superior whitening versus a dissolving hydrogen peroxide whitening strip.

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Apr 25th, 12:00 AM Apr 25th, 12:00 AM

Relative Efficacy of Two Marketed Hydrogen Peroxide Whitening Strips

Signature Grand, Davie, Florida, USA

Objective. Efficacy of two marketed hydrogen peroxide whitening strip regimens was compared in this randomized, examiner-blinded clinical trial. Methods. A total of 57 healthy adult volunteers were randomized to one of the two treatments: Listerine Whitening® Quick Dissolving Strips (LWQD strip) or 6% hydrogen peroxide Crest® Whitestrips® (control strips). Both products were used twice daily for 14 days per manufacturer's instructions: LWQD were worn until completely dissolved and the control strips were worn for 30 min per application. Efficacy was measured objectively as L*a*b* color change using digital images of the maxillary anterior teeth at Baseline, Day 8, and Day 15. Results. The average age of study participants was 42.1 and 63% were females. At Day 8, adjusted mean (SE) Δb* was –0.82 (0.12) for the LWQD strip and –1.32 (0.12) for the control strip while adjusted mean (SE) ΔL* was 0.97 (0.14) and 1.75 (0.14) for the LWQD and the control strips, respectively. At the end-of-treatment at Day 15, adjusted mean (SE) Δb* was –1.50 (0.17) for the LWQD strip and –2.03 (0.16) for the control strip. For ΔL*, end-of-treatment, adjusted means (SE) were 1.33 (0.20) for the LWQD strip compared to 2.06 (0.18) for the control strip. Groups differed significantly for both Δb* and ΔL*at the end-of-treatment (p ≤ 0.03) and at Day 8 (p < 0.005) favoring the control strip. No product-related adverse events were reported. Conclusion. Use of the 6% hydrogen peroxide control strip provided superior whitening versus a dissolving hydrogen peroxide whitening strip.