Recovery of binocular responses by cortical neurons after early monocular lesions

Authors

Yuzo M. Chino, University of HoustonFollow
Earl L. Smith III, University of HoustonFollow
Bin Zhang, University of HoustonFollow
Kazuki Matsuura, University of Houston
Takafumi Mori, University of Houston
Jon H. Kaas, Vanderbilt UniversityFollow

ISSN

1097-6256

Publication Date

1-1-2001

Abstract

A small lesion of the retina in one eye deprives normally binocular neurons in a sector of primary visual cortex of activating inputs from the lesioned eye, but not from the other, intact eye. Here we demonstrate that after monocular lesions early in life followed by years of recovery, deprived cortical neurons become robustly responsive to stimulation via new receptive fields in a zone of preserved retina around the retinal lesion, while maintaining receptive fields for the intact eye. These neurons respond similarly to comparable stimuli in two different locations, possibly producing a local diplopia or blur.

DOI

10.1038/89469

Volume

4

Issue

7

First Page

689

Last Page

690

Disciplines

Optometry

NSUWorks Citation

Chino, Yuzo M.; Smith, Earl L. III; Zhang, Bin; Matsuura, Kazuki; Mori, Takafumi; and Kaas, Jon H., "Recovery of binocular responses by cortical neurons after early monocular lesions" (2001). Faculty Articles. 3.
https://nsuworks.nova.edu/hpd_opt_facarticles/3