Faculty Articles
Dynamics of spatial frequency tuning in mouse visual cortex
ISSN
0022-3077
Publication Date
3-7-2012
Abstract
Neuronal spatial frequency tuning in primary visual cortex (V1) substantially changes over time. In both primates and cats, a shift of the neuron's preferred spatial frequency has been observed from low frequencies early in the response to higher frequencies later in the response. In most cases, this shift is accompanied by a decreased tuning bandwidth. Recently, the mouse has gained attention as a suitable animal model to study the basic mechanisms of visual information processing, demonstrating similarities in basic neuronal response properties between rodents and highly visual mammals. Here we report the results of extracellular single-unit recordings in the anesthetized mouse where we analyzed the dynamics of spatial frequency tuning in V1 and the lateromedial area LM within the lateral extrastriate area V2L. We used a reverse-correlation technique to demonstrate that, as in monkeys and cats, the preferred spatial frequency of mouse V1 neurons shifted from low to higher frequencies later in the response. However, this was not correlated with a clear selectivity increase or enhanced suppression of responses to low spatial frequencies. These results suggest that the neuronal connections responsible for the temporal shift in spatial frequency tuning may considerably differ between mice and monkeys.
DOI
10.1152/jn.00022.2012
Volume
107
Issue
11
First Page
2937
Last Page
2949
Disciplines
Optometry
NSUWorks Citation
Vreysen, Samme; Zhang, Bin; Chino, Yuzo M.; Arckens, Lutgarde; and Van den Bergh, Gert, "Dynamics of spatial frequency tuning in mouse visual cortex" (2012). Faculty Articles. 25.
https://nsuworks.nova.edu/hpd_opt_facarticles/25
