Thrombotic and Hemorrhagic Complications Following Left Ventricular Assist Device Placement: An Emphasis on Gastrointestinal Bleeding, Stroke, and Pump Thrombosis

Authors

Joseph Phan, Nova Southeastern UniversityFollow
Kareem Elgendi, Nova Southeastern UniversityFollow
Masi Javeed, University of South Florida
Juan M. Aranda, University of Florida
Mustafa M. Ahmed, University of Florida
Juan Vilaro, University of Florida
Mohammad Al-Ani, University of Florida
Alex M. Parker, University of Florida

Document Type

Article

Publication Date

12-27-2023

Publication Title

Cureus

Keywords

hemorrhagic complications, thrombotic complications, device-related thrombus (drt), stroke, gastrointestinal bleeding, left ventricular assist device, heart failure

ISSN

2168-8184

Volume

15

Issue/No.

12

First Page

e51160

Abstract

The left ventricular assist device (LVAD) is a mechanical circulatory support device that supports the heart failure patient as a bridge to transplant (BTT) or as a destination therapy for those who have other medical comorbidities or complications that disqualify them from meeting transplant criteria. In patients with severe heart failure, LVAD use has extended survival and improved signs and symptoms of cardiac congestion and low cardiac output, such as dyspnea, fatigue, and exercise intolerance. However, these devices are associated with specific hematologic and thrombotic complications. In this manuscript, we review the common hematologic complications of LVADs.

Comments

Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

NSUWorks Citation

Phan, Joseph; Elgendi, Kareem; Javeed, Masi; Aranda, Juan M.; Ahmed, Mustafa M.; Vilaro, Juan; Al-Ani, Mohammad; and Parker, Alex M., "Thrombotic and Hemorrhagic Complications Following Left Ventricular Assist Device Placement: An Emphasis on Gastrointestinal Bleeding, Stroke, and Pump Thrombosis" (2023). HPD Articles. 427.
https://nsuworks.nova.edu/hpd_facarticles/427

DOI

10.7759/cureus.51160

Copyright

© Copyright 2023 Phan et al.