Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome Caused by Apalutamide: A Case Presentation.

Authors

Gabriella Martin, Nova Southeastern UniversityFollow
Evan Lambert, Nova Southeastern UniversityFollow
Gordon K. Wang, Nova Southeastern University

Document Type

Article

Publication Date

7-11-2023

Publication Title

Cureus

Keywords

apalutamide, drug reaction, eosinophilia, rash, prostate cancer, side effects, medication, dress

ISSN

2168-8184

Volume

15

Issue/No.

7

First Page

e41687

Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe drug reaction that is triggered several weeks after the start of a new medication. This syndrome presents with a variety of clinical symptoms, specifically a manifestation involving a fever followed by a severe rash. A variety of medications are known to trigger DRESS, with the most common being anticonvulsants and allopurinol. Here, we discuss the case of a medication, apalutamide, that caused DRESS in our patient. Early recognition and abrupt discontinuation of the medication is required for the management of this syndrome and to minimize morbidity and mortality.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

NSUWorks Citation

Martin, Gabriella; Lambert, Evan; and Wang, Gordon K., "Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome Caused by Apalutamide: A Case Presentation." (2023). HPD Articles. 343.
https://nsuworks.nova.edu/hpd_facarticles/343

DOI

10.7759/cureus.41687

Copyright

© Copyright 2023 Martin et al.