Document Type
Article
Publication Date
6-27-2023
Publication Title
Pharmaceutics
Keywords
cryogels, biomaterials, biomedical applications, drug delivery, tissue engineering
ISSN
1999-4923
Volume
15
Issue/No.
7
Abstract
Cryogels, composed of synthetic and natural materials, have emerged as versatile biomaterials with applications in tissue engineering, controlled drug delivery, regenerative medicine, and therapeutics. However, optimizing cryogel properties, such as mechanical strength and release profiles, remains challenging. To advance the field, researchers are exploring advanced manufacturing techniques, biomimetic design, and addressing long-term stability. Combination therapies and drug delivery systems using cryogels show promise. In vivo evaluation and clinical trials are crucial for safety and efficacy. Overcoming practical challenges, including scalability, structural integrity, mass transfer constraints, biocompatibility, seamless integration, and cost-effectiveness, is essential. By addressing these challenges, cryogels can transform biomedical applications with innovative biomaterials.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
NSUWorks Citation
Omidian, Hossein; Dey Chowdhury, Sumana; and Babanejad, Niloofar, "Cryogels: Advancing Biomaterials for Transformative Biomedical Applications." (2023). HPD Articles. 341.
https://nsuworks.nova.edu/hpd_facarticles/341
ORCID ID
DOI
10.3390/pharmaceutics15071836
Copyright
© 2023 by the authors.