Adenocarcinoma of an Unknown Primary Site: Presentation, Diagnosis, and Management.

Authors

Jaafar Abou-Ghaida, Nova Southeastern UniversityFollow
Adya A. Ali, Nova Southeastern UniversityFollow
Sheela Anasseri, Nova Southeastern UniversityFollow
Leslie Walker, Broward Health Medical Center
Tye Barber, Broward Health Medical CenterFollow

Document Type

Article

Publication Date

6-28-2023

Publication Title

Cureus

Keywords

mcca, molecular cancer classifier assay, adenocarcinoma, cup, carcinoma of unknown primary

ISSN

2168-8184

Volume

15

Issue/No.

6

First Page

e41074

Abstract

Carcinoma of unknown primary (CUP) is a rare metastatic disease in which a primary tumor site cannot be identified. CUP is a diagnosis of exclusion requiring prior workup to identify a primary site. We present a case of a 64-year-old male with vague abdominal pain, a history of gastroesophageal reflux disease (GERD), gastritis, esophagitis, hepatitis C, alcoholic pancreatitis, liver hemangioma, and Warthin tumor, and family history of cancer that was found to have CUP. The diagnosis was made after an extensive workup was done including serum tumor markers, computed tomography (CT) and ultrasound (US) imaging, flow cytometry, and an array of immunohistochemistry stains positive for only cytokeratin 7.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

NSUWorks Citation

Abou-Ghaida, Jaafar; Ali, Adya A.; Anasseri, Sheela; Walker, Leslie; and Barber, Tye, "Adenocarcinoma of an Unknown Primary Site: Presentation, Diagnosis, and Management." (2023). HPD Articles. 327.
https://nsuworks.nova.edu/hpd_facarticles/327

DOI

10.7759/cureus.41074

Copyright

© Copyright 2023 Abou-Ghaida et al.