Document Type

Article

Publication Date

6-28-2023

Publication Title

Cureus

Keywords

abdominal pain, alcoholic pancreatitis, carcinoma of unknown primary (CUP), computed tomography (CT), cytokeratin 7, diagnosis of exclusion, esophagitis, flow cytometry, gastritis, gastroesophageal reflux disease (GERD), hepatitis C, immunohistochemistry, liver hemangioma, metastatic disease, primary tumor, serum tumor markers, ultrasound imaging, Warthin tumor

ISSN

2168-8184

Volume

15

Issue/No.

6

First Page

e41074

Abstract

Carcinoma of unknown primary (CUP) is a rare metastatic disease in which a primary tumor site cannot be identified. CUP is a diagnosis of exclusion requiring prior workup to identify a primary site. We present a case of a 64-year-old male with vague abdominal pain, a history of gastroesophageal reflux disease (GERD), gastritis, esophagitis, hepatitis C, alcoholic pancreatitis, liver hemangioma, and Warthin tumor, and family history of cancer that was found to have CUP. The diagnosis was made after an extensive workup was done including serum tumor markers, computed tomography (CT) and ultrasound (US) imaging, flow cytometry, and an array of immunohistochemistry stains positive for only cytokeratin 7.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

DOI

10.7759/cureus.41074

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