Document Type

Article

Publication Date

8-10-2023

Publication Title

Journal of Analytical Methods in Chemistry

ISSN

2090-8873

Volume

2023

First Page

3753083

Abstract

OBJECTIVE: Cannabinoid extraction from

METHODS: In this study, we developed rapid, sensitive, selective, accurate, and validated liquid chromatography-tandem mass spectrometry for the quantification of cannabinoids. The methods are for determining 11 cannabinoids in cannabis (hemp) extracted in oil form, and we investigated the accuracy of the labeling and thermal stability regarding the cannabinoids on 17 oil cannabis samples.

RESULTS: In the UPLC chromatogram, we see a good resolution and there is no matrix effect and the accuracy were 98.2% to 102.6%, and the precision was 0.52%-8.18%. The linearity of the calibration curves in methanol was with a regression

CONCLUSION: The validated method proved to be selective, accurate, and precise, with acceptable linearity within the calibration range with no matrix effect. The stability profile data indicated that high temperatures could change the quality of commercial samples.

Comments

The authors would like to express their sincere gratitude to Wingate University for providing support and resources that contributed to the successful completion of this research article

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

DOI

10.1155/2023/3753083

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