Document Type

Article

Publication Date

9-19-2023

Publication Title

Cureus

Keywords

carcinoid-triggered fibrosis, valvular prosthesis, valvular fibrosis, quadruple valve replacement, carcinoid heart disease

ISSN

2168-8184

Volume

15

Issue/No.

9

First Page

e45547

Abstract

This report details a rare case of left-sided carcinoid heart disease (CHD). In CHD, vasoactive substances released from carcinoid tumors cause fibrous tissue formation on the right side of the heart. These substances are usually inactivated by monoamine oxidase A in the lungs, safeguarding the left side of the heart. Exceptions include the presence of a patent foramen ovale (PFO), pulmonary metastasis, or elevated serotonin levels. Intriguingly, our patient exhibited significant left-sided involvement without these factors, ultimately requiring a quadruple valve replacement surgery. After eight months post-operation, the patient is stable with no cardiovascular complications. This rare case of CHD, along with its outcome, hints at potential unidentified etiologies for left-sided CHD and underscores valve replacement as a viable treatment.

Comments

Declaration of generative AI and AI-assisted technologies in the writing process statement: During the preparation of this work, the author(s) used AI-assisted technology, specifically ChatGPT, in order to enhance language usage. After using this tool/service, the author(s) reviewed and edited the content as needed and take(s) full responsibility for the content of the publication.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

DOI

10.7759/cureus.45547

Peer Reviewed

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