What Is Old Is New Again: Delafloxacin, A Modern Fluoroquinolone

Authors

Jonathan C Cho
Matthew P Crotty
Bryan P White
Marylee V. Worley, Nova Southeastern UniversityFollow

Publication Title

Pharmacotherapy

Publisher

John Wiley & Sons, Inc.

ISSN

1875-9114

Publication Date

1-2018

Keywords

administration, adult, anti-bacterial agents, bacterial, fluoroquinolones, gram-negative bacteria, gram-negative bacterial infections, gram-positive bacteria, gram-positive bacterial infections, humans, intravenous, oral, skin diseases

Abstract

Delafloxacin is a new fluoroquinolone antimicrobial approved for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) in adults using dosage regimens of 300 mg intravenously every 12 hours, 450 mg orally every 12 hours, or switching from intravenous to oral regimens for a 5- to 14-day treatment duration. Dosage adjustments in patients with severe renal dysfunction (estimated glomerular filtration rate [eGFR] = 15-29 ml/min/1.73 m

DOI

10.1002/phar.2050

Volume

38

Issue

1

First Page

108

Last Page

121

Disciplines

Medicine and Health Sciences | Pharmacy and Pharmaceutical Sciences

NSUWorks Citation

Cho, Jonathan C; Crotty, Matthew P; White, Bryan P; and Worley, Marylee V., "What Is Old Is New Again: Delafloxacin, A Modern Fluoroquinolone" (2018). Faculty Articles. 62.
https://nsuworks.nova.edu/hpd_corx_facarticles/62