Faculty Articles
Comparative assessment of growth supporting potential of different alginic acid salts
Publication Title
International Journal of Polymeric Materials and Polymeric Biomaterials
Publisher
Taylor & Francis Group
ISSN
1563-535X
Publication Date
2016
Keywords
alginates, cell proliferation, encapsulation
Abstract
This study compares the cell survival of HeLa, osteoblasts (MG 63), and human umbilical cord stem cells (hUMSCs) in three different salts of alginic acid including sodium, potassium, and triethanolamine. While the treatment of the cells with wide range of concentrations of potassium and triethanolamine alginate did not adversely affect the cell growth, higher concentrations of sodium alginate inhibited cell growth on all the cell types tested. Furthermore, the cells encapsulated in potassium alginate beads showed enhanced cell survival compared to the growth in other salts. Our results indicated that potassium alginate can be used with wide varieties of cell types.
DOI
10.1080/00914037.2015.1055630
Volume
65
Issue
1
First Page
47
Last Page
53
Disciplines
Medicine and Health Sciences | Pharmacy and Pharmaceutical Sciences
NSUWorks Citation
Kandalam, Umadevi; Omidian, Hamid; and Mirza, Mudasar, "Comparative assessment of growth supporting potential of different alginic acid salts" (2016). Faculty Articles. 248.
https://nsuworks.nova.edu/hpd_corx_facarticles/248
