Faculty Articles

Title

Angiotensin receptor blocker drugs and inhibition of adrenal beta-arrestin-1-dependent aldosterone production: Implications for heart failure therapy.

Publication Title

World J Cardiol

Volume

9

Issue

3

Publication Date / Copyright Date

3-26-2017

First Page

200

Last Page

206

Abstract

Aldosterone mediates many of the physiological and pathophysiological/cardio-toxic effects of angiotensin II (AngII). Its synthesis and secretion from the zona glomerulosa cells of the adrenal cortex, elevated in chronic heart failure (HF), is induced by AngII type 1 receptors (AT

Disciplines

Medicine and Health Sciences | Pharmacy and Pharmaceutical Sciences

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