Angiotensin receptor blocker drugs and inhibition of adrenal beta-arrestin-1-dependent aldosterone production: Implications for heart failure therapy.

Authors

Anastasios Lymperopoulos, Nova Southeastern UniversityFollow
Beatrix Aukszi

Publication Title

World J Cardiol

Publication Date

3-26-2017

Abstract

Aldosterone mediates many of the physiological and pathophysiological/cardio-toxic effects of angiotensin II (AngII). Its synthesis and secretion from the zona glomerulosa cells of the adrenal cortex, elevated in chronic heart failure (HF), is induced by AngII type 1 receptors (AT

Volume

9

Issue

3

First Page

200

Last Page

206

Disciplines

Medicine and Health Sciences | Pharmacy and Pharmaceutical Sciences

NSUWorks Citation

Lymperopoulos, Anastasios and Aukszi, Beatrix, "Angiotensin receptor blocker drugs and inhibition of adrenal beta-arrestin-1-dependent aldosterone production: Implications for heart failure therapy." (2017). Faculty Articles. 245.
https://nsuworks.nova.edu/hpd_corx_facarticles/245