"Prevalence and correlates of Capgras syndrome in Alzheimer's disease." by Dylan G. Harwood, Warren W. Barker et al.
 

Faculty Articles

Prevalence and correlates of Capgras syndrome in Alzheimer's disease.

Publication Title

International journal of geriatric psychiatry

ISSN

0885-6230

Publication Date

6-1-1999

Keywords

Aged, Aged, 80 and over, Alzheimer Disease, Capgras Syndrome, Cognition Disorders, Cross-Sectional Studies, Delusions, Disease Progression, Female, Humans, Incidence, Male, Outpatients, Prevalence, Psychiatric Status Rating Scales

Abstract

OBJECTIVES: This study examined the prevalence and clinical correlates of Capgras syndrome (CS) in Alzheimer's disease.

DESIGN: Cross-sectional study of elderly patients evaluated at an outpatient memory disorders clinic classified according to the presence or absence of CS.

SUBJECTS: One hundred and fifty-one consecutive patients diagnosed with probable (N=110) or possible (N=48) Alzheimer's disease (AD) utilizing NINCDS-ADRDA diagnostic criteria.

MATERIALS: The Behavioral Pathology in Alzheimer's Disease Rating Scale (BEHAVE-AD), Mini-Mental State Examination (MMSE) and Blessed Dementia Scale (BDS).

RESULTS: CS was observed in 10% of the sample (N=16). Associated factors included other delusions, lower MMSE scores and higher BDS scores. The relation between CS and both cognitive and functional status remained significant after controlling for other delusions.

CONCLUSION: CS was prevalent in approximately 10% of our community-dwelling AD sample. This syndrome was more common at the later stages of the illness and showed relations with increased functional impairment and other psychotic symptomatology.

Volume

14

Issue

6

First Page

415

Last Page

420

Disciplines

Medical Specialties | Medicine and Health Sciences | Osteopathic Medicine and Osteopathy

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