Faculty Articles
Title
Chronic fatigue syndrome: probable pathogenesis and possible treatments
ISBN or ISSN
0012-6667
Publication Title
Drugs
Volume
62
Issue
17
Publication Date / Copyright Date
1-1-2002
First Page
2433
Last Page
2446
Abstract
Chronic fatigue syndrome (CFS) belongs in the medically unexplained illnesses. It affects approximately 0.2-0.7% of the population in Western countries. It is characterised by unexplained fatigue, lasting 6 months or more, impairment of neurocognitive functions and quality of sleep, and of somatic symptoms, such as recurrent sore throat, muscle aches, arthralgias, headache and postexertional malaise. No link between infections and CFS has been clearly established but the immune system is activated, there are aberrations in several hypothalamic-pituitary axes and involvement of other parts of the central nervous system. No specific treatment has been found. Cognitive behavioural therapy is established to be of value to improve quality of life. More effective treatment should result, as advances in biomedical as well as psychological research continue.
Disciplines
Medical Specialties | Medicine and Health Sciences | Osteopathic Medicine and Osteopathy
NSUWorks Citation
Evengard, B. and Klimas, Nancy G., "Chronic fatigue syndrome: probable pathogenesis and possible treatments" (2002). Faculty Articles. 452.
https://nsuworks.nova.edu/hpd_com_faculty_articles/452
