Speaker Credentials
OMS-II
Speaker Credentials
MS
College
Dr. Kiran C. Patel College of Osteopathic Medicine, DO
Medical Specialty
Gastroenterology
Format
Poster
Start Date
November 2024
End Date
November 2024
Track
1
Abstract
Introduction: The obesity epidemic has pushed fatty liver disease to the forefront of the 21st century. Disease identification can be done invasively with a liver biopsy or noninvasively through elastography and measurements of biomarkers. Presently, there are no FDA-approved drugs on the market to treat the disease. Alternative medicinal treatments have been investigated, which include altering the intestinal microbiota and consuming anti-inflammatory, herbal-based, vitamin-based, and plant-based medications. Methods: In this study, multiple databases were used to identify articles pertaining to fatty liver disease (FLD). All articles gathered from the databases were peer-reviewed and less than 10 years old to ensure the credibility of the work and recent information regarding the disease. In all 13 peer-reviewed articles, the diagnosis of FLD was most commonly done by analyzing ALT and AST liver enzymes and lipid profiles. Results: It was observed that anti-inflammatory, herbal-based, vitamin-based, and plant-based medications and healthy gut microbiota had beneficial and therapeutic effects in treating FLD when coupled with healthy lifestyle changes. All medicinal treatments were found to lower the ALT and AST liver enzymes, lipid profiles, and liver steatosis scores in studies where ultrasound was used before and after treatment. Discussion: Further investigation is needed to fully understand the mechanisms behind the therapeutic effects of treating FLD; however, the medicinal treatments discussed in this review show promising prospects for treating the disease. The treatment options studied may have beneficial impacts in treating FLD patients and may be used in the development of future medications to combat the disease.
Emerging Diagnostics and Therapeutics for Non-Alcoholic Fatty Liver Disease
Introduction: The obesity epidemic has pushed fatty liver disease to the forefront of the 21st century. Disease identification can be done invasively with a liver biopsy or noninvasively through elastography and measurements of biomarkers. Presently, there are no FDA-approved drugs on the market to treat the disease. Alternative medicinal treatments have been investigated, which include altering the intestinal microbiota and consuming anti-inflammatory, herbal-based, vitamin-based, and plant-based medications. Methods: In this study, multiple databases were used to identify articles pertaining to fatty liver disease (FLD). All articles gathered from the databases were peer-reviewed and less than 10 years old to ensure the credibility of the work and recent information regarding the disease. In all 13 peer-reviewed articles, the diagnosis of FLD was most commonly done by analyzing ALT and AST liver enzymes and lipid profiles. Results: It was observed that anti-inflammatory, herbal-based, vitamin-based, and plant-based medications and healthy gut microbiota had beneficial and therapeutic effects in treating FLD when coupled with healthy lifestyle changes. All medicinal treatments were found to lower the ALT and AST liver enzymes, lipid profiles, and liver steatosis scores in studies where ultrasound was used before and after treatment. Discussion: Further investigation is needed to fully understand the mechanisms behind the therapeutic effects of treating FLD; however, the medicinal treatments discussed in this review show promising prospects for treating the disease. The treatment options studied may have beneficial impacts in treating FLD patients and may be used in the development of future medications to combat the disease.