Speaker Credentials
MS-IV
College
College of Allopathic Medicine
Medical Specialty
Internal Medicine
Format
Poster
Start Date
November 2024
End Date
November 2024
Track
2
Abstract
Introduction: Acute myeloid leukemia (AML) is a hematological malignancy characterized by the proliferation of undifferentiated hematopoietic stem cells, leading to symptoms like fatigue, fever, and bleeding. While AML can infiltrate various organs, myocardial and pancreatic involvement are extremely rare, with myopericarditis and acute pancreatitis being particularly uncommon. Case Description: A 72-year-old hispanic female with a history of pancreatitis and autoimmune disorders presented with worsening lower abdominal pain, dysuria, nausea, and vomiting. Her pancreatitis resolved, but she subsequently developed chest pain and was diagnosed with acute pericarditis. Her elevated white blood cell count, predominantly monocytic, led to the diagnosis of AML with monocytic predominance. Deviation From the Expected: This case is unique in the uncommon presentation and complications in the setting of AML. Discussion: AML can present with atypical symptoms such as pericarditis or pancreatitis, complicating diagnosis. The limited literature on AML presenting with these rare complications highlights the need for heightened clinical awareness. Conclusion: This case underscores the importance of considering AML in patients with unexplained pericarditis or pancreatitis, particularly when accompanied by abnormal blood counts. This case adds to the limited literature on rare AML presentations, including acute pancreatitis and constrictive pericarditis, and emphasizes the necessity for thorough investigation and early management to improve outcomes in AML patients with atypical symptoms. Grants: No funding or disclosures to report.
Included in
Cardiology Commons, Gastroenterology Commons, Internal Medicine Commons, Oncology Commons
When AML Strikes Twice: A Case of Acute Myeloid Leukemia with Concurrent Myopericarditis and Acute Pancreatitis
Introduction: Acute myeloid leukemia (AML) is a hematological malignancy characterized by the proliferation of undifferentiated hematopoietic stem cells, leading to symptoms like fatigue, fever, and bleeding. While AML can infiltrate various organs, myocardial and pancreatic involvement are extremely rare, with myopericarditis and acute pancreatitis being particularly uncommon. Case Description: A 72-year-old hispanic female with a history of pancreatitis and autoimmune disorders presented with worsening lower abdominal pain, dysuria, nausea, and vomiting. Her pancreatitis resolved, but she subsequently developed chest pain and was diagnosed with acute pericarditis. Her elevated white blood cell count, predominantly monocytic, led to the diagnosis of AML with monocytic predominance. Deviation From the Expected: This case is unique in the uncommon presentation and complications in the setting of AML. Discussion: AML can present with atypical symptoms such as pericarditis or pancreatitis, complicating diagnosis. The limited literature on AML presenting with these rare complications highlights the need for heightened clinical awareness. Conclusion: This case underscores the importance of considering AML in patients with unexplained pericarditis or pancreatitis, particularly when accompanied by abnormal blood counts. This case adds to the limited literature on rare AML presentations, including acute pancreatitis and constrictive pericarditis, and emphasizes the necessity for thorough investigation and early management to improve outcomes in AML patients with atypical symptoms. Grants: No funding or disclosures to report.