Speaker Credentials

OMS-II

Speaker Credentials

BS

College

Dr. Kiran C. Patel College of Osteopathic Medicine, DO

Medical Specialty

Psychiatry

Format

Poster

Start Date

November 2024

End Date

November 2024

Track

4

Abstract

Objective: This study evaluated measures of motor performance as predictors of medication adherence in older adults with HIV infection. Background: Patient adherence to HIV treatment is crucial for optimal clinical outcomes. Factors such as the complexity of drug regimens and financial constraints make ideal adherence difficult. While strategies promoting adherence exist, there is a lack of research on screenings that predict adherence. Previous research suggests motor performance is correlated with adherence but has not been extensively studied in older individuals. The integration of motor assessments into screenings of medication adherence may help to improve outcomes. Methods: Data were drawn from a study evaluating cognitive training for mild neurocognitive disorder in 46 patients 50 years of age or older with HIV. Motor performance was assessed with the 10-Meter Walk Test (10MWT) and the Grooved Pegboard test (PegR). Medication adherence was measured using the Gonzalez/Lu self-report adherence questionnaire. Correlation and regression analyses including race, gender, and age were carried out using the Statistical Package for the Social Sciences, version 28 (Armonk, NY: IBM). Results: 10MWT and PegR were significantly related to adherence (both p < 0.001). Regression analysis accounting for confounding variables (age, gender, race) suggests 10MWT is a more representative indicator of adherence (multiple R2 adjusted for confounders = 0.33 vs R2 = 0.22). Conclusion: Walking speed was correlated with medication adherence in older adults with HIV, suggesting the potential usefulness of this measure in assessing risk for poor medication adherence. Grants: Supported by a grant from the National Institute on Aging to Dr. Ownby (R21AG056256).

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Nov 13th, 11:00 AM Nov 13th, 11:08 AM

Association Between Motor Tests and Antiretroviral Medication Adherence in Older Adults With HIV

Objective: This study evaluated measures of motor performance as predictors of medication adherence in older adults with HIV infection. Background: Patient adherence to HIV treatment is crucial for optimal clinical outcomes. Factors such as the complexity of drug regimens and financial constraints make ideal adherence difficult. While strategies promoting adherence exist, there is a lack of research on screenings that predict adherence. Previous research suggests motor performance is correlated with adherence but has not been extensively studied in older individuals. The integration of motor assessments into screenings of medication adherence may help to improve outcomes. Methods: Data were drawn from a study evaluating cognitive training for mild neurocognitive disorder in 46 patients 50 years of age or older with HIV. Motor performance was assessed with the 10-Meter Walk Test (10MWT) and the Grooved Pegboard test (PegR). Medication adherence was measured using the Gonzalez/Lu self-report adherence questionnaire. Correlation and regression analyses including race, gender, and age were carried out using the Statistical Package for the Social Sciences, version 28 (Armonk, NY: IBM). Results: 10MWT and PegR were significantly related to adherence (both p < 0.001). Regression analysis accounting for confounding variables (age, gender, race) suggests 10MWT is a more representative indicator of adherence (multiple R2 adjusted for confounders = 0.33 vs R2 = 0.22). Conclusion: Walking speed was correlated with medication adherence in older adults with HIV, suggesting the potential usefulness of this measure in assessing risk for poor medication adherence. Grants: Supported by a grant from the National Institute on Aging to Dr. Ownby (R21AG056256).