Comparison of Bacterial Meningitis Complicated by Stroke in Adults versus Children: A Scoping Review

Speaker Credentials

OMS-III

Speaker Credentials

BS

College

Dr. Kiran C. Patel College of Osteopathic Medicine, DO

Medical Specialty

Infectious Disease

Format

Poster

Start Date

November 2024

End Date

November 2024

Track

1

Abstract

Title: Comparison of Bacterial Meningitis Complicated by Stroke in Adults versus Children: A Scoping Review Authors: Isabella Cook, OMS-II; Apurva Ramanujam, OMS-II; Afrida Sara, OMS-II; Arjun Nair, OMS-II; Sabina Chon, OMS-II, M.S.; Erick Boldt, OMS-II; Miranda Londono, OMS-II; Alan Wang, OMS-II, M.A.; Sarah Mohamed, OMS-II; Shivani Dave, OMS-II; Yuri Zagvazdin, Ph.D. Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, Florida Background: Bacterial meningitis (BM) complicated by stroke in adults include distinct manifestations compared to children. Although there are notable differences in presentations between children and adults, there is limited availability in research defining a protocol for differences in management and treatment in adults and children.

Objective: The objective of this study is to compare the causes, presentation, comorbidities, complications, risk factors, hospital outcomes, and resource utilization associated with bacterial meningitis complicated by stroke between the pediatric and adult population.

Methods: This study was designed as a scoping review for bacterial meningitis complicated by stroke selecting articles using the following criteria: 1) Patients are children 0-18 years old or adults 18 years and older 2) Patients have a confirmed diagnosis of bacterial meningitis and suffered a sequelae of stroke 3) Patients who experienced a stroke prior to acquiring BM or who are already being treated for a prior stroke will be excluded. 10 articles were included to compare pediatric and adult management. Results: Pediatric infarction cases often manifested with basal ganglia and cortex involvement, prolonged fever, seizures, and hyponatremia. However, adult cases showed more focal neurological signs upon admission.

Conclusion: The results of this study show that the presentation of BM complicated by stroke is variable depending on age, gender, clinical manifestations, and comorbidities. Education on these subtle differences can lead to earlier recognition, prompt referral, and timely intervention, ultimately improving patient outcomes. Treatment in pediatric populations is currently being explored as current guidelines derive from the treatment of adult populations.

This document is currently not available here.

Share

COinS
 
Nov 13th, 9:08 AM Nov 13th, 9:16 AM

Comparison of Bacterial Meningitis Complicated by Stroke in Adults versus Children: A Scoping Review

Title: Comparison of Bacterial Meningitis Complicated by Stroke in Adults versus Children: A Scoping Review Authors: Isabella Cook, OMS-II; Apurva Ramanujam, OMS-II; Afrida Sara, OMS-II; Arjun Nair, OMS-II; Sabina Chon, OMS-II, M.S.; Erick Boldt, OMS-II; Miranda Londono, OMS-II; Alan Wang, OMS-II, M.A.; Sarah Mohamed, OMS-II; Shivani Dave, OMS-II; Yuri Zagvazdin, Ph.D. Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, Florida Background: Bacterial meningitis (BM) complicated by stroke in adults include distinct manifestations compared to children. Although there are notable differences in presentations between children and adults, there is limited availability in research defining a protocol for differences in management and treatment in adults and children.

Objective: The objective of this study is to compare the causes, presentation, comorbidities, complications, risk factors, hospital outcomes, and resource utilization associated with bacterial meningitis complicated by stroke between the pediatric and adult population.

Methods: This study was designed as a scoping review for bacterial meningitis complicated by stroke selecting articles using the following criteria: 1) Patients are children 0-18 years old or adults 18 years and older 2) Patients have a confirmed diagnosis of bacterial meningitis and suffered a sequelae of stroke 3) Patients who experienced a stroke prior to acquiring BM or who are already being treated for a prior stroke will be excluded. 10 articles were included to compare pediatric and adult management. Results: Pediatric infarction cases often manifested with basal ganglia and cortex involvement, prolonged fever, seizures, and hyponatremia. However, adult cases showed more focal neurological signs upon admission.

Conclusion: The results of this study show that the presentation of BM complicated by stroke is variable depending on age, gender, clinical manifestations, and comorbidities. Education on these subtle differences can lead to earlier recognition, prompt referral, and timely intervention, ultimately improving patient outcomes. Treatment in pediatric populations is currently being explored as current guidelines derive from the treatment of adult populations.