Faculty Articles

Document Type

Article

Publication Date

8-21-2023

Publication Title

Research Directs in Health Sciences

ISSN or ISBN

2768-492X

Volume

3

Issue/Number

1

ISSN

2768-492X

Abstract/Excerpt

Introduction: While the effects of long-term measures of inflammation and stress are well studied, less is known about the effects of an acute exercise challenge on exercise in young healthy individuals. Methods: This was a randomized crossover design (mean age = 19.25, SD = 1.45)that measured biomarkers of stress (cortisoland salivary alpha amylase, sAA)and inflammation (IL-1β, CRP)in an exercise and control condition. In the exercise condition, participants walked or ran on a treadmill at 75-85% of their maximum heart rate for 40minutes. Under the control condition, participants stood for 40 minutes to control for orthostatic effects. Biomarkers were quantified from saliva collected before, 1 minute after, and 45minutes after the exercise and control condition. Results: The change in biomarkers from baseline values (+1min and + 45min) between exercise and control conditions showed that compared to the control condition, the acute exercise bout significantly increased sAA CRP at +1minat +45min and in IL-1β+45min. Cortisol levels significantly decreased at both time points in the control condition Conclusions: Ultimately, the results of this study show how small and realistically achievable amounts of exercise can acutely strengthen the body’s physiological responses to immune challenges.

DOI

10.53520/rdhs2023.10486

ORCID ID

0000-0003-2187-245X, 0000-0002-8930-1058

Comments

The authors would like to thank Milan Patel and Diane Woodbine for their assistance.

Copyright, 2023 by the authors.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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