Faculty Articles

A Survey Study of Neuropsychiatric Complaints in Patients with Graves’ Disease: A Reassessment of Self-Reported Symptoms and Current Practice 20 Years Later: Graves‘ Disease and Thyroid Foundation [Kindle Edition]

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It has been estimated that 1 in 200 people or 1.6 million individuals suffer from Graves' disease in the United States alone. Despite this, the United States Preventative Services Task Force concluded that there is insufficient evidence to support for regular screening for thyroid dysfunction in non-pregnant, asymptomatic adults. The task force specifically cited a lack of prospective research in their decision making. However, a number of investigation, including a study conducted by Stern and colleagues in 1996, suggest that symptoms associated with Graves disease are multidimensional and may include neuropsychiatric, as well as somatic symptoms that may be difficult to detect, but may be life threatening. The present investigation represents an extensive twenty-year follow-up to the Stern et al. survey study conducted over 20 years ago. In addition to examining the neuropsychiatric complaints of Graves’ disease patients, the current investigation also examined issues related to the diagnosis and treatment of the disorder. Research conducted by our group suggests that Graves' disease continues to be misdiagnosed at an alarming rate and that access to healthcare and health information, as well as inadequate routine screening, may play a role in misdiagnosis and a delay in treatment.