College of Psychology: Faculty Articles

Title

Water Bridging Dynamics of Polymerase Chain Reaction in the Gauge Theory Paradigm of Quantum Fields

Document Type

Article

Publication Date

5-11-2017

Keywords

water bridging, dipole waves, coherent states, polymerase chain reaction, DNA amplification, DNA transduction, enzyme catalytic activity, fractal-like self-similarity

Publication Title

Water

ISSN

2073-4441

Volume

9

Issue/No.

5

Abstract

We discuss the role of water bridging the DNA-enzyme interaction by resorting to recent results showing that London dispersion forces between delocalized electrons of base pairs of DNA are responsible for the formation of dipole modes that can be recognized by Taq polymerase. We describe the dynamic origin of the high efficiency and precise targeting of Taq activity in PCR. The spatiotemporal distribution of interaction couplings, frequencies, amplitudes, and phase modulations comprise a pattern of fields which constitutes the electromagnetic image of DNA in the surrounding water, which is what the polymerase enzyme actually recognizes in the DNA water environment. The experimental realization of PCR amplification, achieved through replacement of the DNA template by the treatment of pure water with electromagnetic signals recorded from viral and bacterial DNA solutions, is found consistent with the gauge theory paradigm of quantum fields.

Comments

Addendum published on 17 June 2017, see Water 2017, 9(6), 436.

DOI

https://doi.org/10.3390/w9050339

Peer Reviewed

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