Chemistry and Physics Faculty Articles
Title
Hyperbranched Bisphosphonate‐Functional Polymers via Self‐Condensing Vinyl Polymerization and Postpolymerization Multicomponent Reactions
Document Type
Article
Publication Date
12-4-2020
Publication Title
Macromolecular Rapid Communications
Keywords
bisphosphonates, Kabachnik‐Fields, multicomponent reactions, RAFT, self‐condensing‐vinyl polymerization
ISSN
1521-3927
Volume
42
First Page
2000578
Abstract
The synthesis of hyperbranched aminobisphosphonic acid polymers via reversible addition‐fragmentation chain transfer (RAFT) self‐condensing vinyl polymerization is reported. A novel acrylamide‐functional chain transfer monomer is synthesized and characterized by 1H and 13C NMR spectroscopy, elemental analysis, and mass spectrometry. The monomer is subsequently copolymerized with an acrylamide monomer bearing a pendent amine group to create hyperbranched amine‐functional polymers with degrees of branching dictated by changing the reaction stoichiometry. The aminobisphosphonate functional group is introduced via a 3‐component Kabachnik‐Fields reaction. An alternate functionalization of the amine polymers to create acid‐degradable imine hydrogels is also employed. This work demonstrates the application of multicomponent reactions to RAFT‐derived hyperbranched polymers and provides a new route to previously inaccessible polymers.
NSUWorks Citation
Calvo, P. R., Sparks, C. A., Hochberg, J., Wagner, K. B., & Sumerlin, B. S. (2020). Hyperbranched Bisphosphonate‐Functional Polymers via Self‐Condensing Vinyl Polymerization and Postpolymerization Multicomponent Reactions. Macromolecular Rapid Communications, 42, 2000578 - . https://doi.org/10.1002/marc.202000578. Retrieved from https://nsuworks.nova.edu/cnso_chemphys_facarticles/289
Supporting Information
ORCID ID
0000-0002-7836-7262
DOI
10.1002/marc.202000578
