Chemistry and Physics Faculty Articles
Title
Hyperbranched Poly(N-(2-hydroxypropyl) methacrylamide) via RAFT Self-Condensing Vinyl Polymerization
Document Type
Article
Publication Date
3-21-2016
Publication Title
Polymer Chemistry
ISSN
1759-9962
Volume
7
Issue/No.
11
First Page
2099
Last Page
2014
Abstract
We report the first synthesis of hyperbranched poly(N-(2-hydroxypropyl) methacrylamide) (HB-PHPMA) using reversible addition–fragmentation chain transfer (RAFT) self-condensing vinyl polymerization (SCVP). The synthesis of these complex, well-defined architectures involved the copolymerization of HPMA with a chain transfer monomer (CTM). The polymerization kinetics, as well as the effects of initiator concentration and the ratio of monomer to CTM were studied. The resulting polymers show high molecular weights and controlled branching frequencies. Due to their inherent amphiphilic nature, these hyperbranched structures self-assemble into aggregates in water. Additionally, we determined the cloud point of the HB-PHPMA to be in the range of sub-ambient temperature to 40 °C. This approach provides access to a new class of thermoresponsive PHPMA polymers with potential to be used in drug delivery and other biological applications.
NSUWorks Citation
Alfurhood, J. A., Sun, H., Bachler, P. R., & Sumerlin, B. S. (2016). Hyperbranched Poly(N-(2-hydroxypropyl) methacrylamide) via RAFT Self-Condensing Vinyl Polymerization. Polymer Chemistry, 7, (11), 2099 - 2014. https://doi.org/10.1039/C6PY00111D. Retrieved from https://nsuworks.nova.edu/cnso_chemphys_facarticles/214
ORCID ID
0000-0002-7836-7262
DOI
10.1039/C6PY00111D
Comments
©Royal Society of Chemistry 2016