Detecting Reaction Intermediates in Liquids on the Millisecond Time Scale Using Desorption Electrospray Ionization

Authors

Richard H. Perry, Stanford UniversityFollow
Maurizio Splendore, Stanford University
Allis Chien, Stanford University
Nick K. Davis, Stanford University
Richard N. Zare, Stanford University

Document Type

Article

Publication Title

Angewandte Chemie International Edition

ISSN

1433-7851

Publication Date

1-3-2011

Keywords

Mass spectrometry, Organometallic catalysis, Reaction intermediates, Ruthenium, Transfer hydrogenation

Abstract

Capturing transient species: The bombardment of a surface‐bound Ru^II complex with charged droplets containing a ligand allows the detection of reaction intermediates (see figure). The reaction investigated is used to synthesize Ru^II catalysts containing amino alcohol ligands, which facilitate the asymmetric transfer hydrogenation of ketones and imines.

DOI

10.1002/anie.201004861

Volume

50

Issue

1

First Page

250

Last Page

254

Comments

©2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim

Additional Comments

Air Force Office of Scientific Research grant #: FA 9550‐10‐1‐0235

NSUWorks Citation

Perry, R. H., Splendore, M., Chien, A., Davis, N. K., & Zare, R. N. (2011). Detecting Reaction Intermediates in Liquids on the Millisecond Time Scale Using Desorption Electrospray Ionization. Angewandte Chemie International Edition, 50, (1), 250 - 254. https://doi.org/10.1002/anie.201004861. Retrieved from https://nsuworks.nova.edu/cnso_chemphys_facarticles/188